Clinical Trials Logo
  1. Home
  2. Ventricular Arrythmia
  3. NCT05964660
  4. Details
NCT05964660 Clinical Trial

Echocardiography-based Motion Integration and Management for Substrate Characterization and STAR Therapy in Ventricular Tachycardias

Ventricular Arrythmia Clinical Trial

— MATRIX-VT  

Official title:
New 3D-echocardiography-based Motion Integration and mAnagement for subsTrate characteRisation and Stereotactic Arrhythmia radIoablation tX in Ventricular Tachycardias- the MATRIX-VT Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05964660
Other study ID # MATRIX-VT
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date August 2023
Est. completion date June 2024

Study information
Verified date July 2023
Source University of Luebeck
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Prospective, observational, single center, pilot study to analyze the feasibility of motion and structural data integration in patients with ventricular arrhythmia by means of artificial intelligence for improved arrhythmogenic substrate characterization and motion management during stereotactic arrhythmia radioablation.

Description:

This is a prospective, observational, single center, pilot study. Data from preprocedural contrast-enhanced cardiac computed tomography and optically-tracked 3D transthoracic echocardiography of patients receiving catheter ablation for ventricular arrhythmia will be analyzed by means of artificial intelligence in order to better characterize the ventricular arrhythmogenic substrate and to improve the definition methods of the planning target volume during the stereotactic arrhythmia radioablation therapy by integrating the motion data into volume demarcation.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 20
Est. completion date June 2024
Est. primary completion date June 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria: - Age = 18 years - Indication for catheter ablation of ventricular arrhythmias (ventricular fibrillation, ventricular tachycardia, premature ventricular contractions) - Indication for preprocedural contrast-enhanced cardiac computed tomography for cardiac structure characterization Exclusion Criteria: - Platelet count < 100,000 cells/mm3 - BMI > 45 kg/m2 or < 18 kg/m2

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Germany Klinik für Rhythmologie Luebeck Schleswig-Holstein

Sponsors (2)
Lead Sponsor Collaborator
University of Luebeck Institute for Robotics and Cognitive Systems, University of Luebeck

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Feasibility of algorithm training to achieve improved arrhythmogenic substrate characterization The feasibility of training the artificial intelligence-based algorithm using the preprocedural contrast-enhanced cardiac computed tomography and optically-tracked 3D transthoracic echocardiography data to better define the ventricular arrhythmogenic substrate in patients exhibiting ventricular arrhythmias. 1 month after complete data collection
Primary Feasibility of algorithm training to improve the planning target volume definition for stereotactic arrhythmia radioablation therapy The feasibility of training the artificial intelligence-based algorithm using the preprocedural contrast-enhanced cardiac computed tomography and optically-tracked 3D transthoracic echocardiography data to better define the planning target volume for stereotactic arrhythmia radioablation therapy 1 month after complete data collection
See also
  Status Clinical Trial Phase
Completed NCT05791032 - Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study N/A
Not yet recruiting NCT06063811 - Ventricular Tachycardia Ablation in LVAD Patients
Withdrawn NCT05049720 - ExtraVascular Implantable Cardiac Defibrillator Continued Access Study N/A
Completed NCT04060680 - Extravascular ICD Pivotal Study N/A
Not yet recruiting NCT04990089 - VIVO European Observational Registry
Recruiting NCT05418036 - Safety Assessment for Sotalol Protocol in Outpatient Unit Phase 4
Recruiting NCT04264455 - Evaluation of Long-term Incidence of Ventricular Arrhythmias in Patients With Acute Myocarditis
Recruiting NCT03821051 - China Structural Ventricular Arrhythmias Registry
Recruiting NCT03880708 - China Inherited Ventricular Arrhythmias Registry
Recruiting NCT03041519 - Zero-fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for the Treatment of Ventricular Arrhythmias N/A
Completed NCT03204981 - Intramural Needle Ablation for the Treatment of Refractory Ventricular Arrhythmias N/A
Recruiting NCT04239144 - Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease N/A
Recruiting NCT05829993 - Development of an Artificial Intelligence Algorithm to Detect Pathological Repolarization Disorders on the ECG and the Risk of Ventricular Arrhythmias
Recruiting NCT05707637 - Bipolar Radio-frequency Ablation After Standard Unipolar Approach - Prospective Registry.
Completed NCT05357716 - Preliminary Research Evaluation for Ambulatory Leadless Electrocardiogram Recorder Trial
Recruiting NCT06158698 - CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine Phase 3
Active, not recruiting NCT03495297 - A Randomised Trial of S-ICD Implantation With and Without Defibrillation Testing N/A
Recruiting NCT06378996 - Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring N/A
Not yet recruiting NCT06360939 - Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease N/A
Suspended NCT03502499 - Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation N/A