Ventral Hernia Clinical Trial
Official title:
Negative Pressure Incisional Wound Therapy for High-risk Ventral Hernia Repair: a Randomized Controlled Trial
The investigators are testing the ability of vacuum dressings to improve wound healing for patients having large hernias surgically repaired who are at risk of having wound complications. The trial will randomly be giving some patients having this surgery the vacuum dressing and some a standard dressing and observing how their wounds heal in hospital and at follow-up appointments.
This study is a multicentre, clinical randomized controlled trial comparing the use of incisional negative pressure wound therapy versus standard sterile dressings in high-risk ventral hernia repairs. The trial will be enrolling patients undergoing elective or emergent ventral hernia repair who have risk factors for surgical wound complications and randomizing them to either receive a PREVENA incisional negative pressure wound therapy system dressing for 7 days post-operatively or a standard sterile dressing.for 2 days post-operatively. The primary outcome will be a composite of a variety of surgical site complications including wound infection, dehiscence, seroma / hematoma formation, non-healing wound, early hernia recurrence, and fistula formation. These will be evaluated by unblinded clinical judgement of treating physicians, and blinded assessment with ultrasonography. Secondary outcomes will include perceived difference in Quality of Life and cost-effectiveness of the intervention. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06016426 -
Mass Closure vs Layer by Layer Closure
|
N/A | |
| Recruiting |
NCT05572021 -
A Comparison of the Outcomes in Fortiva and Strattice Mesh
|
N/A | |
| Completed |
NCT02263599 -
Conservative Treatment For Ventral Hernia
|
||
| Completed |
NCT02292264 -
Risk Factors and Complications of Ventral Hernia Repair
|
||
| Completed |
NCT02263625 -
Regional Differences In Indication for Ventral Hernia Repair
|
||
| Completed |
NCT01961687 -
A Prospective, Multi-Center Study of Phasix™ Mesh for Ventral or Incisional Hernia Repair.
|
N/A | |
| Completed |
NCT01325246 -
Reoperation Rate Versus Clinical Recurrence After Ventral Hernia Repair
|
N/A | |
| Completed |
NCT03283982 -
Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
|
N/A | |
| Not yet recruiting |
NCT05526209 -
Longitudinal Relaxing Incision as a Technique for Recurrence Prevention in Ventral Hernia
|
||
| Completed |
NCT04438369 -
Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
|
N/A | |
| Recruiting |
NCT04173884 -
Video-based Collaborative Learning to Improve Ventral Hernia Repair
|
N/A | |
| Recruiting |
NCT02703662 -
Performance of Biologic Mesh Materials in Abdominal Wall Reconstruction
|
Phase 2/Phase 3 | |
| Completed |
NCT03938688 -
Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation
|
N/A | |
| Completed |
NCT01719718 -
The Influence of Closing the Gap on Postoperative Seroma and Recurrences in Laparoscopic Ventral Hernia Repair
|
N/A | |
| Completed |
NCT03342040 -
Transverse Abdominis Plane Block in Laparoscopic Ventral Hernia Repair
|
N/A | |
| Completed |
NCT04150796 -
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
|
N/A | |
| Recruiting |
NCT03222102 -
Ventral Hernia Prevention After Liver Transplantation
|
N/A | |
| Completed |
NCT05610267 -
Gentrix® Surgical Matrix for Soft Tissue Reinforcement in Ventral Hernia Repair
|
||
| Terminated |
NCT01794338 -
The Use of Biologic Mesh vs Bioabsorbable Mesh During Ventral Hernia Repair in At-risk Patients
|
N/A | |
| Completed |
NCT01886963 -
A Clinical Trial Using Spy Elite System in Planning Tissue Advancement Flaps After Ventral Hernia Repair
|
N/A |