Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT06437561 |
| Other study ID # |
114099 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
February 13, 2024 |
| Est. completion date |
March 15, 2024 |
Study information
| Verified date |
May 2024 |
| Source |
Golestan University of Medical sciences |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Venous aneurysms are not common in general, but because of the inherent risk of thrombosis in
aneurysms, their timely diagnosis and treatment are recommended in most of the current
sources. Ten cases of venous aneurysms were diagnosed and managed in our vascular surgery
department from October 2018 to January 2024. Patient information was extracted from their
files retrospectively.
Description:
A vascular aneurysm is defined as the focal dilatation of a vessel. Aneurysm is classically
used for arterial dilatations, although dilatations can occur in any part of the vascular
system including veins. Venous aneurysms are not common in general, but with the increase in
the use of duplex ultrasound, the number of cases diagnosed with venous aneurysms has
recently increased. Venous aneurysms are more common in the lower limbs, and in the lower
limbs, the involvement of the deep venous system is much more than the superficial venous
system. According to reports, 77% of venous aneurysms are present in the lower limbs, of
which 57% are in the deep venous system and 1.5% in the superficial venous system.
Considering their rarity, venous aneurysms may cause diagnostic challenges in some cases.
The importance of these aneurysms, especially in the lower limbs, which inherently have
relative stasis due to the opposite flow direction of gravity, is that by creating venous
stasis and whirlwind blood flow inside the aneurysm, they increase the susceptibility to
clotting. Also, due to dysfunction of the pigeon nest valves, they cause chronic venous
insufficiency. Although clot formation and subsequent pulmonary embolism are more common in
deep venous aneurysms, cases of pulmonary embolism secondary to superficial venous aneurysms
of the lower limbs have also been reported.
Complications caused by chronic venous insufficiency are more common in aneurysms that occur
at the main junctions of superficial and deep veins, including saphenous femoral and
saphenous popliteal junctions.
Considering the possible complications mentioned about venous aneurysms, these aneurysms need
treatment, regardless of their location, and although in the superficial system, surgical
resection is the most commonly recommended method, other surgical methods such as
aneurysmectomy and primary repair, resection, and graft interposition, and also endovascular
methods have been used. Of course, in case of insufficiency in the venous system, specific
treatment of the cause of insufficiency (such as stripping of the large saphenous vein) is
necessary in addition to the treatment of the aneurysm.
Regarding the follow-up after the treatment of aneurysms of the superficial system, most
articles have recommended short-term treatment with anticoagulants and control of the
superficial and deep systems through color doppler.
In this case series, we present 10 cases of venous aneurysms and discuss their presentation,
diagnosis, and management.
