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Varicose Ulcer clinical trials

View clinical trials related to Varicose Ulcer.

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NCT ID: NCT05364112 Recruiting - Varicose Ulcer Clinical Trials

Utilization of Compreflex Wraps in Patients With Chronic Venous Insuffciency

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This is a multicentre, quasi-experimental study to evaluate the Conformitè Europëenne-marked Compreflex standard calf and foot (with basic liner) under routine conditions. The study will be conducted at 4 clinics and will include 100 consecutive patients. Patients will be followed-up until 26 weeks.

NCT ID: NCT05322525 Recruiting - Clinical trials for Venous Leg Ulcers (VLU)

A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment of Venous Leg Ulcers.

Start date: June 23, 2021
Phase: Phase 4
Study type: Interventional

A Research Study to evaluate the safety and potential efficacy of ON101 cream for the treatment of venous leg ulcers.The objectives of the study are to determine the safety and to explore the potential efficacy of ON101 cream in patients with venous leg ulcers.

NCT ID: NCT05319106 Recruiting - Venous Leg Ulcer Clinical Trials

Phase Ⅱ Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Venous Leg

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

This project adopts a prospective clinical trial study to compare and evaluate the efficacy of local transplantation of human umbilical cord mesenchymal stem cells combined with silver ion dressing and simple silver ion dressing in the treatment of venous lower extremity ulcer wounds. To improve the healing rate and quality of life of patients.

NCT ID: NCT05311124 Recruiting - Pressure Ulcer Clinical Trials

Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This study is to determine if large, full thickness scalp wounds with exposed calvarium resulting from acutely created extirpative defects can be reliably and durably resurfaced with IDRT without burring or fenestration as a preliminary step, regardless of the size of the calvarial defect.

NCT ID: NCT05291169 Recruiting - Venous Leg Ulcer Clinical Trials

Omeza Combination Therapy With Standard of Care to Standard of Care Alone for Chronic Venous Leg Ulcers

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

A Randomized, Multicenter, Open Label Study Comparing Omeza Combination Therapy with Standard of Care to Standard of Care alone for Chronic Venous Leg Ulcers over the course of 4 weeks

NCT ID: NCT05241704 Recruiting - Varicose Ulcer Clinical Trials

Endovenous Ablation Combined With Fat Grafting for Venous Ulcers

Start date: February 2022
Phase: N/A
Study type: Interventional

The aim of this trial is to determine if fat grafting may have applicability to venous ulcers by comparing healing and recurrence rates in patients who receive combined fat grafting and endovenous ablation with patients who receive endovenous ablation only

NCT ID: NCT05239416 Recruiting - Varicose Ulcer Clinical Trials

Fat Grafting in Reducing Recurrence in Patients With Healed Venous Ulcers A Prospective Randomised Clinical Pilot Study

Start date: February 2022
Phase: N/A
Study type: Interventional

In this study, investigators aim to use fat grafting in patients with previously healed venous ulcers to study its role on increasing skin thickness and reconstructing skin layers which was damaged by venous hypertension and determine its impact on reducing recurrence rates at 1 year

NCT ID: NCT05170984 Recruiting - Diabetic Foot Ulcer Clinical Trials

MAtrix Therapy for Hard-to-heal ChrOnic Wounds

MATHCOW
Start date: February 10, 2022
Phase: N/A
Study type: Interventional

CACIPLIQ20® is currently a class III CE marked medical device available in various European and non-European countries, and currently primarily used in managing hard-to-heal wounds. This study is a prospective and standardized recording of patients' data followed in real-life conditions to appreciate the benefits of a therapeutic strategy including CACIPLIQ20® use. It also aims at collecting data to follow-up the device's efficacy and safety and estimate its cost-effectiveness.

NCT ID: NCT05165459 Recruiting - Venous Leg Ulcer Clinical Trials

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers

Start date: November 29, 2021
Phase: N/A
Study type: Interventional

To evaluate the efficacy and safety of Cytori Celution System in Hungarian patients with chronic non-healing venous leg ulcers.

NCT ID: NCT05134597 Recruiting - Inflammation Clinical Trials

Gene Expression in Chronic Venous Leg Ulcers

GECVELUS
Start date: January 1, 2021
Phase:
Study type: Observational

Chronic Venous Disease (CVD) is a widespread clinical condition widely spread in the western countries that may negatively impact the quality of life (QoL) of affected patients. Chronic venous leg ulcers (CVLUs) are the most severe form of CVD, and several genetic and molecular alterations have been studied in order to understand the progression of CVD towards CLVUs. Chronic inflammation is a key element in CVLUs onset, and recently T helper 17 (Th-17) cells, a subtype of pro-inflammatory T helper (CD4+) cells defined by the production of a cytokine signature of which IL-17 represents the progenitor, seem to be related to several chronic disease. The aim of this study is to evaluate Th17- Gene Expression profile in patients with CVD and CVLUs.