the Effect of Different Modialites of Varicocelectomy on Semen Parameters

Status Not yet recruiting

Clinical Trial Summary

to evalute the effect inguinal and subinguinal approach of varicoceclectomy on semen parameter for patients complaining of varicocele with normal semen parameter (pain is the main complaint)

Clinical Trial Description

the varicocele is defined as dilated and incompetent veins within the pampiniform plexus of spermatic cord. varicocele has been described as the most common surgically correctable cause of male subinfertility.this is a disease that devolops during puberty when both endocrine and exocrine function of the testicle dramatically increases, along with testicular blood flow. varicocele only rarely detected in boys less than 10 years. left sided varicocle found in 15% of healthy young men.incontrast, the incidence in sub fertile men approaches 40% bilateral varicocele is uncommon in healthy men (less than 10%) but palpated in 20% in sub fertile men. in-general varicocele don't spontaneously regress. an accurate physical examination remain the corner stone of varicocele diagnosis.

several anatomic features contribute to the predominance of left sided varicocele is the left intrnal spermatic vein longer than the right and it typically joins the left renal vein at a right angle.as result of this character higher venous pressures fair transmited to the left spermatic vein and result in reterograde reflux of blood.

varicocle are associated with testicular atrophhy and varicocle correction can reverse atrophy in adolececnt. there is strong evidence affect semen quality it can cause abnormalties in concentration, motility and morphology.main defect is the motility.

indication of varicocelectomy:

1. Large varicoceles in adolescents

2. Childhood varicocele with testicular atrophy

3. Varicoceles with elevated FSH values, or low testosterone levels

4. Varicoceles with scrotal pain

5. Cosmetic indication

6. Male infertility with pathological semen analysis and varicocele ;

Study Design

Related Conditions & MeSH terms

Varicocele

Clinical Trial Details

NCT number	NCT03281915
Study type	Observational
Source	Assiut University
Contact	Abdelrahman M Abdelkader
Phone	01068336396
Email	abdelrahmanmohamed.aa@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	October 15, 2017
Completion date	October 15, 2018

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00639899` - The Effect of Spermatic Vein Embolization on Prostatic Hypertrophy	N/A
Recruiting	`NCT03540056` - Testicular Growth During Puberty in Boys With and Without a Left-sided Varicocele
Completed	`NCT02983656` - Analysis on AEFI Surveillance Data for Live Attenuated Varicella Vaccine	N/A
Enrolling by invitation	`NCT05617261` - Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective Study
Not yet recruiting	`NCT05330533` - Effect of Recent Ejaculation on Scrotal Duplex Parameters in Infertile Males With Varicocele
Not yet recruiting	`NCT03090438` - IVF Outcomes After Varicocele Repair	N/A
Completed	`NCT02401087` - The Anaesthesiological Approach to Varicocele Correction in Outpatients Setting: an Observational Analysis
Completed	`NCT00044369` - Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele	N/A
Completed	`NCT05034406` - The Effect of Subcutaneous and Intraperitoneal Anesthesia on Post Laparoscopic Pain	N/A
Completed	`NCT03477149` - EASYX-1 : A Multicenter Study on Safety and Efficacy of Easyx Liquid Embolization Agent Used in Five Separate Indications	N/A
Not yet recruiting	`NCT05171504` - Lactoferrin and Iron in Seminal Plasma of Varicocele
Completed	`NCT02335385` - Single Incision Laparoscopic Varicocelectomy	N/A
Not yet recruiting	`NCT03341897` - Varicocele Treatement by Endovasculer Embolization	N/A
Active, not recruiting	`NCT03079609` - The Search for Viral and Bacterial Etiology of Varicocele	N/A
Not yet recruiting	`NCT02719093` - Role of FSHR Polymorphism p.N680S in the Therapy With FSH in Patients Who Underwent Varicocele Surgery	Phase 4
Enrolling by invitation	`NCT02033863` - Evaluation of PerformanCe of the Peripheral EOS in the Treatment of Varicocele or Pelvic Congestion SynDromE	N/A
Recruiting	`NCT02695199` - Doppler Ultrasound Assisted Varicocelectomy Improve Sperm Qualities	N/A
Recruiting	`NCT02304575` - Quality of Life Among Testicular Cancer Survivors	N/A
Completed	`NCT01463787` - Comparison of Outcomes of Two Approaches in Microsurgical Varicocelectomy in Chinese Infertile Males: A Prospective Randomized, Controlled Trial	Phase 4
Completed	`NCT01259258` - Dye Assisted Lymphatic Sparing Subinguinal Varicocelectomy	Phase 2

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms