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Vaping clinical trials

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NCT ID: NCT04854616 Completed - Smoking Cessation Clinical Trials

Cessation of Smoking Trial in the Emergency Department

CoSTED
Start date: January 4, 2022
Phase: N/A
Study type: Interventional

The Cessation of Smoking Trial in the Emergency Department (CoSTED) is an National Institute for Health Research (NIHR) Health Technology Assessment (HTA) funded randomised controlled trial (RCT). The research question is "in people attending the Emergency Department who smoke, does a brief intervention (including the provision of an electronic cigarette (e-cigarette) and referral to stop smoking services) increase smoking cessation in comparison with usual care and is it cost effective?" The trial includes an internal pilot, health economic evaluation and process evaluation. The primary outcome is smoking cessation, self-reported as continuous smoking abstinence, biochemically validated by carbon monoxide monitoring with cut off of ≥8ppm. The sample size is 972 (486 in intervention and control) across 6 sites.

NCT ID: NCT04836455 Completed - Vaping Clinical Trials

Impact of Vaping Prevention Advertisements

Start date: July 3, 2021
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled trial is to determine whether exposure to vaping prevention advertisements (ads) reduce susceptibility to vaping among adolescents. Previous studies have been informative, but they have tended to be one-time experimental studies that do not replicate the repeated exposures to ads that people have in the real world. This study addresses this issue by repeatedly exposing participants to vaping prevention ads over time. Participants will be adolescents aged 13-17 who currently vape or who are susceptible to vaping. Participants will be randomly assigned to ad stimuli. They will be assigned to one of two The Real Cost trial arms-health harms or addiction-or to a control trial arm (probability of assignment is 1/3 for all trial arms). Participants in the study will take 4 online surveys over a 3-week period, once per week (At week 0, 1, 2, and 3). All participants will view randomized ad stimuli based on their trial arm and answer surveys items at each session.

NCT ID: NCT04568395 Completed - Inflammation Clinical Trials

Acute Effects of TCIG vs ECIG in PLWH

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization and inflammation/oxidative stress.

NCT ID: NCT04522362 Completed - Vaping Clinical Trials

Modeling Stress-precipitated Vaping Behavior

Start date: October 25, 2017
Phase: N/A
Study type: Interventional

The primary aims of this pilot study were to (1) initially validate the applicability of a human laboratory model of relapse initially developed for smokers to e-cigarette users; (2) to use this human laboratory model of lapse behavior to examine the effects of acute psychological stress on vaping-lapse behavior among adults who are experienced, e-cigarette users.

NCT ID: NCT04450537 Completed - Vaping Clinical Trials

PACE Vape Messaging Study

Start date: June 23, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of exposure to vape education messages on beliefs, perceptions, norms, and behaviors related to electronic vapor product use.

NCT ID: NCT04399031 Completed - Cigarette Smoking Clinical Trials

Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco product use; and (2) facilitate adult smokers switching to e-cigarettes. There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile. For this substudy, young adult vapers (N=100) and adult smokers (N=100) will attend one laboratory session in which they will self-administer e-cigarette products varied according to within-subject e-cigarette factors (e.g., flavor, nicotine formulation).

NCT ID: NCT04150510 Completed - Alcohol Drinking Clinical Trials

Assessment of Smoking, Vaping, and Alcohol Consumption Behavior

Start date: February 1, 2020
Phase:
Study type: Observational

To assess smoking, vaping, and alcohol consumption behaviors via online surveys in the population. Further, the objective is to administer additional surveys to assess which methods (e.g., pen-and-paper records, a smartphone app) for monitoring smoking, vaping, alcohol intake, and food intake are preferred by the study population.

NCT ID: NCT04054765 Completed - Vaping Clinical Trials

A Virtual Reality Videogame for E-cigarette Prevention in Teens

Start date: October 17, 2019
Phase: N/A
Study type: Interventional

The use of the Invite Only VR, with the aim to prevent the initiation of e-cigarette use in teens by increasing their knowledge, decreasing their intentions to use e-cigarettes, influencing their harm perceptions and attitudes associated with e-cigarettes, and increasing self-efficacy associated with refusing peers involving e-cigarettes.

NCT ID: NCT04053868 Completed - Tobacco Smoking Clinical Trials

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

Start date: December 9, 2019
Phase: N/A
Study type: Interventional

This is an observational, crossover design that will examine the pharmacokinetics and pharmacodynamics of impact of smoking tobacco cigarettes or vaping the JUUL electronic cigarette.

NCT ID: NCT03379740 Completed - Vaping Clinical Trials

Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants

Start date: July 11, 2017
Phase: N/A
Study type: Interventional

This is a single-center, open-label, concentration-ranging study to evaluate the nicotine PK profile and PD effects in healthy adult experienced users of closed tank/cartridge e-cigarettes using four different variants of P4M3 (nicotine concentration of 1.7%, 1.7% with 1.1% lactic acid [LA], 3% with 1.1% LA, and 4% with 2% LA) or their own e-cigarettes.