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Clinical Trial Summary

Transvaginal pelvic mesh implantation(TVM) is a foreign body implantation operation with intraoperative colonization of vaginal bacteria. However, the vaginal microbiome-host interaction and its influence in the mechanism of mesh exposure after TVM remains unclear. This study will enroll post-TVM patients with and without mesh exposure and use their vaginal swabs to perform TRACE-seq and cytokine analysis. The microbiome-host interactions related with mesh exposure and the changes in protein expression will be analyzed.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05000112
Study type Observational
Source Peking Union Medical College Hospital
Contact Zhibo Zhang
Phone 13693317164
Email zzbspace@126.com
Status Not yet recruiting
Phase
Start date September 2021
Completion date September 2024

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