Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High

Status Completed

Clinical Trial Summary

A case control trial Patients who meet the inclusion criteria were asked to participate in the study and a written consent was obtained from each patient after explaining thoroughly the nature and the scope of the study. Patients were divided into three equal groups: Group A: included 40 pregnant patients. They received two ml of normal saline intravenously as a placebo. Group B: included 40 pregnant patients. They received (20mg) hyoscine butylbromide (one ml HBB+ one ml saline) intravenously. Group C: included 40 pregnant patients .They received two ml (40 mg) hyoscine butylbromide intravenously (HBB).

Clinical Trial Description

A case control trial Patients who meet the inclusion criteria were asked to participate in the study and a written consent was obtained from each patient after explaining thoroughly the nature and the scope of the study. For each patient: 1. Complete history was taking to exclude allergy to hyoscine butylbromide, medical disorders with pregnancy (preeclampsia, diabetes mellitus, heart disease …etc.) and any contraindication for vaginal delivery. 2. General examination of the patients including (pulse, blood pressure, temperature). 3. Obstetric Abdominal examination including fetal lie, fetal presentation, head station and uterine contractions. 4. Vaginal examination including cervical dilatation, effacement and position, state of fetal membranes, presenting part, position of fetal head and pelvic adequacy. 5. Obstetric ultrasound to detect fetal gestational age, fetal birth weight amount of liquor, site of placental attachment and fetal heart rate. Patients were divided into three equal groups: Group A: included 40 pregnant patients. They received two ml of normal saline intravenously as a placebo. Group B: included 40 pregnant patients. They received (20mg) hyoscine butylbromide (one ml HBB+ one ml saline) intravenously. Group C: included 40 pregnant patients .They received two ml (40 mg) hyoscine butylbromide intravenously (HBB). ;

Study Design

Related Conditions & MeSH terms

Vaginal Delivery

Clinical Trial Details

NCT number	NCT03055390
Study type	Interventional
Source	Cairo University
Contact
Status	Completed
Phase	Phase 4
Start date	February 11, 2017
Completion date	February 3, 2022

View Details

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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms