Tranexamic Acid as an Intervention in Abruptio Placenta

Status Completed

Clinical Trial Summary

Abruptio placenta is one of the common causes of antepartum haemorrhage which is more common in the second half of pregnancy and causes a high maternal and neonatal morbidity and mortality

Clinical Trial Description

Abruption has been estimated to occur in 6.5 pregnancies per 1000 births, with an associated perinatal mortality rate of 119 per 1000 in the United States. A Cochrane database study revealed that there is no evidence from trials to show the best way to help pregnant women and their fetuses when there is a placental abruption. The baby may need to be delivered immediately, by cesarean section if alive, and often vaginally if the baby has died. Treatments include pain relief, blood transfusion, and monitoring. Bleeding during pregnancy is characterized by activation of the fibrinolytic system. Tranexamic acid is a potent pharmaceutical agent that suppresses fibrinolysis and thus can be used for managing hemorrhage in pregnancy. The FDA's pregnancy category for tranexamic acid is category B. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05840471
Study type	Interventional
Source	Hawler Medical University
Contact
Status	Completed
Phase	N/A
Start date	January 10, 2023
Completion date	February 10, 2024

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