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Vaccine Hesitancy clinical trials

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NCT ID: NCT06155877 Completed - Clinical trials for Health Knowledge, Attitudes, Practice

Testing The Effectiveness Of Two Interventions To Reduce Vaccine Hesitancy Among Adolescents

Kidivax
Start date: November 15, 2022
Phase: N/A
Study type: Interventional

Vaccines currently prevent several million deaths every year and more lives could be saved if vaccination take up increased. The World Health Organization identifies vaccine hesitancy as one of the ten most important threats to global health and emphasizes the importance of devising interventions to reduce vaccine hesitancy. The two most promising interventions rely on consensus messaging, which has robust but small effects, and interactive discussion, which has larger effects, but is difficult to scale up. School-based interventions aimed at adolescents have the potential to make the best of both types of interventions. Interventions that take place in schools can be conducted over longer periods of time (up to several hours) and are rolled out by a figure that is typically trusted and respected (the teacher). Moreover, intervening during adolescence is particularly timely since important vaccines are delivered at that age (most notably the human papillomavirus vaccine), and because attitudes towards vaccination during adolescence might have a long-lasting impact, as is the case for other health related attitudes. This study tests the effectiveness of two interventions, a pedagogical intervention based on consensus messaging, and a chatbot intervention designed to mimic interactive discussion, on 9th grade French pupils.

NCT ID: NCT06124131 Completed - COVID-19 Clinical Trials

Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening

BENEFIT-C
Start date: November 11, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer screening. The main questions it aims to answer are: - Do patient financial incentives for completing colorectal cancer screening increase screening completion? - Does a patient financial incentive for colorectal cancer screening offered alongside patient financial incentives for COVID-19 and flu shots increase completion of those shots? Participants who are due for colorectal cancer screening will receive telephone outreach from primary care staff who will offer a stool-based colorectal cancer screening. Participants will be randomly assigned to either Group 1 or Group 2. Group 1 participants will be offered financial incentives for completing COVID-19 and flu shots within 2 months of enrollment. Group 2 participants will be offered financial incentives for completing a COVID-19 shot, a flu shot, and colorectal cancer screening within 2 months of enrollment. Researchers will compare to see if completion of a COVID-19 shot, a flu shot, and colorectal cancer screening is different between the two groups.

NCT ID: NCT05994820 Completed - Vaccine Hesitancy Clinical Trials

Chatbot-based Intervention to Promote Vaccine Acceptance in Varansi, India

Start date: September 26, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn compare the efficacy Chatbot messaging directed to parents of infants and children living in unstable urban housing (UUH) in Varansi, India. The main questions it aims to answer are: 1) Can a Chatbot intervention be used to improve attitudes towards childhood vaccines? 2) Does an intervention in which vaccination is presented in the larger context of well-being improve attitudes towards vaccination?

NCT ID: NCT05582564 Completed - Vaccine Hesitancy Clinical Trials

The Effect of Newspaper Reporting on COVID-19 Vaccine Hesitancy: a Randomised Controlled Trial

COVANEW
Start date: June 2, 2021
Phase: N/A
Study type: Interventional

COVID-19 vaccine hesitancy can be observed at different rates in different countries. 1,068 people were surveyed in France and Italy to inquire about individual potential acceptance, focusing on time preferences, in a risk-return framework: having the vaccination today, in a month, and in 3 months; perceived risks of vaccination and COVID-19; and expected benefit of the vaccine. A randomized controlled trial was conducted to understand how everyday stimuli, such as fact-based news about vaccines, impact on audience acceptance of vaccination. The main experiment involved two groups of participants and two different articles about vaccine-related thrombosis taken from two Italian newspapers. One article used a more abstract description and language, and the other used a more anecdotical description and concrete language; each group read only one of these articles. Two other groups were assigned categorization tasks; one was asked to complete a concrete categorization task and the other an abstract categorization task.

NCT ID: NCT05537441 Completed - Influenza Clinical Trials

Precision Vaccine Promotion in Underserved Populations

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

Previous studies have shown that low-cost, behavioral nudges through texting can increase influenza vaccination uptake compared to usual care. However, there are limited studies that evaluate the effect of decreasing barriers to scheduling, especially within safety net populations. The setting for this study, DHS, is the second largest public delivery system in the country and serves approximately half a million diverse patients that are eligible for vaccinations annually. This pilot study (one arm in a larger randomized controlled trial) will examine the effect of text messages highlighting MediCal health plan transportation resources (vs standard text messaging) on influenza vaccination rates in adults during the 2022-2023 flu season.

NCT ID: NCT05532592 Completed - Vaccine Hesitancy Clinical Trials

Investigation on the Hesitancy of COVID-19 Vaccination Among Liver Transplant Recipients in China

Start date: April 27, 2022
Phase:
Study type: Observational

On WeChat platform, through a point-to-point connection, and carry on the questionnaire survey to collect information of liver transplant recipients followed-up by the department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University. Patients meeting inclusion and exclusion criteria will be selected. Conduct statistical analysis to describe the incidence of adverse reactions related to COVID-19 vaccine after liver transplantation, and to compare and evaluate the factors leading to COVID-19 vaccine hesitancy.

NCT ID: NCT05530044 Completed - Vaccine Hesitancy Clinical Trials

Messaging Strategies to Increase Peer Education on COVID-19 Vaccination and Climate Change

Start date: August 30, 2022
Phase: N/A
Study type: Interventional

The primary objective of this protocol is to develop and evaluate peer communication interventions to encourage peer education around COVID-19 vaccination and climate change.

NCT ID: NCT05425823 Completed - Vaccine Hesitancy Clinical Trials

Intervention to Promote Childhood Vaccinations and Influence Vaccination Attitudes

Start date: July 4, 2022
Phase: N/A
Study type: Interventional

This study aims to determine the effect of pregnant women aged 18 years and older who have completed their 28th week of pregnancy and received intervention based on the Health Belief Model, on encouraging childhood vaccinations and influencing their vaccination attitudes, compared to pregnant women who receive standard care group. The 12-month vaccination rate of newborns and the change in their attitudes will be determined according to the Public Attitude Towards Vaccination Scale - Health Belief Model.

NCT ID: NCT05390697 Completed - Vaccine Hesitancy Clinical Trials

Educational Videos to Address Vaccine Hesitancy in Childhood Immunization

Start date: June 18, 2021
Phase: N/A
Study type: Interventional

Vaccine hesitancy and the COVID-19 pandemic may threaten immunization coverage in children. This study aimed to evaluate the tailored educational videos to reduce vaccine hesitancy and analyze immunization completeness status. The investigators conducted an interventional quasi-experimental study in three subdistricts of North Jakarta, Indonesia. Participants were allocated into the intervention and control groups, and the Parent Attitudes about Childhood Vaccines (PACV) questionnaire was used to assess vaccine hesitancy status before and after the intervention.

NCT ID: NCT05206669 Completed - Vaccine Hesitancy Clinical Trials

Testing Messages to Promote HPV Vaccination

Start date: November 18, 2016
Phase: N/A
Study type: Interventional

Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Hispanic women have the highest rates of HPV-related cervical cancer compared to all other groups in the U.S. Previous research has delineated several unique barriers to HPV vaccination among Hispanic women, suggesting that interventions that focus on addressing these barriers may improve HPV vaccination compliance in this population. To address some of these unique barriers, an online tailored messaging intervention was developed and tested. Initial analyses demonstrate that participants exposed to an online intervention demonstrated higher intentions to vaccinate for HPV after viewing the informational materials. The next phase of the project will be comprised of promoting use of the online intervention to the general public through the use of theory-based, pretested messages delivered via advertisements on Facebook and Twitter. Specifically, messages will be targeted based on differences between Hispanic parents of adolescents and Hispanic young adults. Previous research has explored the use of the Extended Parallel Processing Model as a theory to guide messages designed to promote health behaviors. The current study extends this work in the area of HPV prevention. Specifically, it seeks to examine the use of this theory as a means to stimulate information seeking behavior in the form of use of the previously developed online intervention that provides information about HPV. We also hope to make a significant contribution to research demonstrating the importance of targeting messages based on differences in population characteristics. Additionally, this study seeks to build on research examining the use of social media sites as a means for implementing health interventions and promoting positive health outcomes. Ultimately, the current study seeks to improve both the HPV vaccination decision-making process and HPV vaccination rates. If this was achieved among the Hispanic population it could substantially decrease disparities in cervical cancer and other HPV-related diseases.