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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01983488
Other study ID # LIGS10201
Secondary ID
Status Completed
Phase
First received
Last updated
Start date September 2011
Est. completion date December 1, 2019

Study information

Verified date February 2021
Source Moorfields Eye Hospital NHS Foundation Trust
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study is aimed at investigating the long term clinical outcome of patients with uveitis.


Description:

Patients will be included if they are treated for uveitis and have had repeat follow-up. Data will be gathered from the entire length of the patients follow-up. The main outcome measures will be: Change from baseline of Best corrected visual acuity (BCVA)at 10 years Causes of vision loss (≤6/15, VL) and severe vision loss (≤6/60, SVL) at 10 years Number of clinical visits at 10 years.


Recruitment information / eligibility

Status Completed
Enrollment 231
Est. completion date December 1, 2019
Est. primary completion date December 1, 2018
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Clinical Diagnosis of Uveitis. Exclusion Criteria: - No follow-up data.

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
United Kingdom Moorfields Eye Hospital London

Sponsors (1)

Lead Sponsor Collaborator
Moorfields Eye Hospital NHS Foundation Trust

Country where clinical trial is conducted

United Kingdom, 

References & Publications (2)

Bodaghi B, Cassoux N, Wechsler B, Hannouche D, Fardeau C, Papo T, Huong DL, Piette JC, LeHoang P. Chronic severe uveitis: etiology and visual outcome in 927 patients from a single center. Medicine (Baltimore). 2001 Jul;80(4):263-70. — View Citation

Rothova A, Suttorp-van Schulten MS, Frits Treffers W, Kijlstra A. Causes and frequency of blindness in patients with intraocular inflammatory disease. Br J Ophthalmol. 1996 Apr;80(4):332-6. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Best Corrected Visual Acuity Recorded repeat best corrected visual acuity at intervals throughout the length of follow-up. up to 10 years
Secondary Causes of visual loss Record any ocular changes related to permanent visual loss under 6/12 and severe visual loss under 6/60. First follow-up, years 1,2,5,10, Final follow-up
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