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Uveitis, Posterior clinical trials

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NCT ID: NCT03606733 Recruiting - Clinical trials for Diabetic Macular Edema, Cystoid Macular Edema, Chorodial Neovascularzation, Posterior Uveitis

Suprachoroidal Injection of Triamcinolone Acetonide Using Custom Made Needle to Treat Retinal Disorders

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Injection in the Suprachoroidal space has potential of increasing the efficacy of the drug upto six times with direct effect on retinal tissues sparing the crystalline lens and trabecular meshwork.

NCT ID: NCT03598452 Completed - Infection Viral Clinical Trials

High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients

Start date: January 2014
Phase: N/A
Study type: Interventional

This prospective, non-randomized, non-controlled clinical trial was conducted to examine the clinical outcomes achieved by using initial high-dose intravitreal ganciclovir injections of ganciclovir in treating cytomegalovirus (CMV) retinitis in patients without human immunodeficiency virus (HIV) infection.

NCT ID: NCT03145025 Completed - Uveitis, Posterior Clinical Trials

Corneal Endothelial Cell Density in Eyes Treated With a Fluocinolone Acetonide Intravitreal Implant

Start date: July 14, 2017
Phase:
Study type: Observational

An Observational Change-From-Baseline Evaluation of Corneal Endothelial Cell Density in Eyes Treated with a Fluocinolone Acetonide Intravitreal Implant

NCT ID: NCT03097315 Completed - Uveitis Clinical Trials

Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis

AZALEA
Start date: April 4, 2017
Phase: Phase 3
Study type: Interventional

This open-label study is designed to evaluate the safety of suprachoroidally administered triamcinolone acetone injectable suspension, CLS-TA, in patients with non-infectious uveitis with and without macular edema.

NCT ID: NCT03066869 Recruiting - Uveitis, Posterior Clinical Trials

Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis

Start date: March 22, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the short- and long-term efficacy and safety of Acthar for the treatment of adults with non-infectious retinal vasculitis.

NCT ID: NCT02952001 Completed - Uveitis Clinical Trials

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

Start date: December 13, 2017
Phase:
Study type: Observational

This study is a non-interventional, observational extension of the Parent study, CLS1001-301 (NCT02595398). The purpose of this study is to characterize the continued clinical benefit(s) regarding safety and efficacy of suprachoroidally administered CLS-TA, triamcinolone acetonide injectable suspension, for the treatment of macular edema associated with non-infectious uveitis.

NCT ID: NCT02764697 Completed - Uveitis Clinical Trials

Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients

Start date: June 30, 2016
Phase: Phase 4
Study type: Interventional

Uveitis represents a heterogeneous group of diseases that results from ocular inflammatory reaction involving ocular tissue and vasculature. The inflammation usually causes pain, redness, photophobia and blurred vision. This inflammation, is typically treated with regional or systemic therapy. The regional therapy typically consists of topical corticosteroids or periocular or regional corticosteroids. Regional therapy can lead to a steroid response glaucoma, which is increased intraocular pressure.This pilot study aims to evaluate the possible effectiveness of H.P. Acthar in patients with active ocular inflammatory disease, and currently on treatment for glaucoma or have a history of glaucoma.

NCT ID: NCT02746991 Completed - Panuveitis Clinical Trials

Safety and Efficacy Study of a FAI Insert in Subjects With Chronic Non-infectious Posterior Uveitis

Start date: June 2, 2015
Phase: Phase 3
Study type: Interventional

Phase 3, multi-center, randomized, masked, controlled study to evaluate the safety and efficacy of an injectable fluocinolone acetonide intravitreal (FAI) insert for the management of subjects with chronic non-infectious uveitis affecting the posterior segment of the eye. Patients will be randomized to receive either a sham injection or the FAI insert and will be observed for three years following treatment.

NCT ID: NCT02595398 Completed - Uveitis Clinical Trials

Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis

PEACHTREE
Start date: November 17, 2015
Phase: Phase 3
Study type: Interventional

The study is designed to evaluate the safety and efficacy of suprachoroidally administered triamcinolone acetonide, CLS-TA, in subjects with macular edema associated with non-infectious uveitis.

NCT ID: NCT02255032 Completed - Macular Edema Clinical Trials

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis

DOGWOOD
Start date: October 2014
Phase: Phase 2
Study type: Interventional

The study is designed to evaluate the safety and efficacy of triamcinolone acetonide, CLS-TA, in subjects with macular edema following non-infectious uveitis. A single suprachoroidal injection of one of two doses of CLS-TA will each be evaluated in subjects with macular edema following non-infectious uveitis.