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Clinical Trial Summary

This study is designed to determine the minimum effective dose (ED90) of infusions of oxytocin for the prevention of uterine atony / postpartum hemorrhage and the need for additional uterotonics, in low risk parturients presenting for an elective CD.

The primary outcome measure is the response of effective uterine contraction as either satisfactory or unsatisfactory as determined by the obstetrician blinded to the oxytocin infusion dose. Secondary outcomes will include need for additional uterotonics, calculated intra-operative blood loss and presence of oxytocin related adverse effects.


Clinical Trial Description

n/a


Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT00785395
Study type Interventional
Source IWK Health Centre
Contact
Status Completed
Phase Phase 4
Start date June 2008
Completion date August 2008

See also
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Completed NCT00790062 - Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT Phase 4
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Completed NCT03867383 - Calcium Chloride for Prevention of Uterine Atony During Cesarean Phase 1/Phase 2
Active, not recruiting NCT03584854 - Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial Phase 4
Completed NCT02780245 - Role of Tranexamic Acid Versus Uterine Cooling at Caesarean Section Phase 4
Withdrawn NCT03303235 - Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections Early Phase 1
Completed NCT02229513 - Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage N/A
Not yet recruiting NCT06192836 - Placental Removal Method And Uterine Massage On Preventing Postpartum Hemorrhage
Recruiting NCT03413917 - Exploration and Determination of Genomic Markers Predictive of Uterine Atony
Withdrawn NCT01252342 - Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery? Phase 4
Completed NCT04690153 - Novel Approach of Hayman Uterine Compression Sutures for Management of Severe Atonic Postpartum Hemorrhage: Three Vertical Sutures
Completed NCT05027048 - Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery Phase 3
Completed NCT01630187 - Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section Phase 4
Completed NCT01549223 - Oxytocin And Uterotonic Agent Use For Cesarean Delivery Phase 4