Up-Down Oxytocin Infusion

Status Completed

Clinical Trial Summary

This study is designed to determine the minimum effective dose (ED90) of infusions of oxytocin for the prevention of uterine atony / postpartum hemorrhage and the need for additional uterotonics, in low risk parturients presenting for an elective CD.

The primary outcome measure is the response of effective uterine contraction as either satisfactory or unsatisfactory as determined by the obstetrician blinded to the oxytocin infusion dose. Secondary outcomes will include need for additional uterotonics, calculated intra-operative blood loss and presence of oxytocin related adverse effects.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00785395
Study type	Interventional
Source	IWK Health Centre
Contact
Status	Completed
Phase	Phase 4
Start date	June 2008
Completion date	August 2008

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See also
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Completed	`NCT02229513` - Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage	N/A
Not yet recruiting	`NCT06192836` - Placental Removal Method And Uterine Massage On Preventing Postpartum Hemorrhage
Recruiting	`NCT03413917` - Exploration and Determination of Genomic Markers Predictive of Uterine Atony
Withdrawn	`NCT01252342` - Does Intramyometrial Oxytocin Improve Outcome in Elective Cesarean Delivery?	Phase 4
Completed	`NCT04690153` - Novel Approach of Hayman Uterine Compression Sutures for Management of Severe Atonic Postpartum Hemorrhage: Three Vertical Sutures
Completed	`NCT05027048` - Calcium Chloride for Prevention of Blood Loss During Intrapartum Cesarean Delivery	Phase 3
Completed	`NCT01630187` - Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section	Phase 4
Completed	`NCT01549223` - Oxytocin And Uterotonic Agent Use For Cesarean Delivery	Phase 4