Lime Powder Regimen (LPR) for Prevention of Renal Stone Recurrence

Status Completed

Clinical Trial Summary

Lime powder regimen (LPR) is a lime-derived composition enriches with citrate/citric acid and potassium. LPR was invented to treat the renal stone patients with high risk of stone recurrence after stone removal. LPR should have equal or higher efficacy and lower adverse effect than current standard medicine.

Clinical Trial Description

Lime powder regimen (LPR) is a mixture of lime-derive component with adjuvants containing high concentration of citrate, and moderate amount of potassium, magnesium and antioxidants. LPR was tested and verified to be very less toxic in cell culture and animal models. The clinical trial phase II showed that LPR reduced urinary metabolic abnormalities that enhance stone formation, such as hypocitraturia, hypokaliuria and acidified urine. Adverse effect of LPR was very low. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03258190
Study type	Interventional
Source	Chulalongkorn University
Contact
Status	Completed
Phase	Phase 2
Start date	July 1, 2014
Completion date	June 30, 2018

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