Urinary Tract Infections Clinical Trial
Official title:
Communication and Compliance With Guidelines for Antibiotic Prescribing by General Practice to Nursing Home Residents With Suspected Urinary Tract Infections -A Research Protocol for a Cross-Sectional Study in the Primary Care Sector
Antibiotic resistance is becoming a bigger problem. If the problem remains unsolved, the WHO
predicts a return to the pre-antibiotic era. Overtreatment with antibiotics drives
development of resistant bacteria and adverse events in patients, thus identification and
rectifying factors leading to unnecessary antibiotic prescriptions are a public health
problem.
Urinary Tract Infections (UTIs) are the most commonly diagnosed infection in nursing homes
(NH). A prevalence study showed that in up to 76% of all antibiotic prescriptions in Danish
NHs the indication was UTI. In this particular group of patients with suspected UTI, the
literature has repeatedly shown that a vast amount of these antibiotic courses are
inappropriate.
As people age, the prevalence of asymptomatic bacteriuria increases significantly.
Asymptomatic bacteriuria is a condition that should not be treated with antibiotics. Thus,
the treatment decision in this group should not rely on the result of urinary testing and
should only commence, when classical urinary symptoms are present. Urinary testing of NH
residents is one of the drivers of overtreatment. Therefore, a recent Danish guideline from
Institute of Rational Pharmacology (IRF) on elderly with suspected UTI suggest that urine
culture should only be performed when typical urinary symptoms are present and that
antibiotic prescribing should be delayed until the result of the culture is available
whenever possible. It is unknown to what extent Danish GPs follows these guidelines.
NH residents are often immobile, therefore; the diagnostic process of UTI in NH residents
differs from the norm, which could also explain some part of the inappropriate prescribing.
Immobility introduces physical distance between patient and GP because the patient is unable
to visit the General Practitioners office. Because home visits are rare, when a UTI is
suspected, NH staff usually contacts the GP in writing, over the phone and occasionally in
person to relate the patient history and physical findings.
When another link in the communication chain between patient and GP is added, clinical
information passes through additional health professionals and the risk of communication
error and misunderstanding increases. Some forms of communications may be more suited to fit
this setting than others. When communicating in person, it is possible to take non-verbal
cues into account and immediately clear up insecurities. Communication by phone eliminates
non-verbal cues, but a dialog about unclarified aspects is still attainable. Written
communication, however, has none of the clarifying traits of the former, and to elaborate on
the content the GP will have to contact the NH, which takes time in an already packed
schedule.
The investigators hypothesize that the more direct the contact form, the better the quality
of clinical information, which leads to increased compliance with guidelines. Thus by proxy,
our hypothesis becomes that compliance to guidelines increases with directness of contact
form. The aim of this study is to investigate to which degree the guidelines on antibiotic
prescribing for NH residents with suspected UTI are followed and how the communication form
affects adherence to guidelines.
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