Effect of Chlorhexidine on Bacteriuria

Status Recruiting

Clinical Trial Summary

This study is conducted to determine and compare the effect of applying Povidone-iodine and Chlorhexidine solutions for perinea washing on bacteriuria rate and type in patients with urinary catheter in intensive care unit.

Clinical Trial Description

This is a double blind randomized study with control group. The population is patients in intensive care unit of Shahid Beheshti hospital of Babol city. Main include criteria are 18-55 years old, need to having urine catheter for 10 days at least and no urinary infection in catheterization time. Main exclude criteria are appearing genital wound, allergic or dermatitis disorders. Sample size include 105 patients dividing in three equal groups of Povidone-iodine, Chlorhexidine and Normal saline randomly. Interventions are Washing perinea area and catheter first 5 centimeters by 15 ml of Povidone-iodine 10%, Chlorhexidine .2% or Normal saline .9%, 3 times a day for 10 days. Urine analysis are performed in days 1,3,5,7 and 9 after catheterization and urine cultures are performed in days 5 and 10 after catheterization for detection of bacteriuria and microorganism type. ;

Study Design

Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02032394
Study type	Interventional
Source	Mashhad University of Medical Sciences
Contact	Seyedreza Mazlooum, Head
Phone	+985118591511
Email	mazlomr@mums.ac.ir
Status	Recruiting
Phase	Phase 4
Start date	July 2013
Completion date	April 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03235947` - Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients	Phase 4
Terminated	`NCT02198833` - Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection	N/A
Withdrawn	`NCT01881165` - Cranberry on Urinary Tract Infections	Phase 4
Completed	`NCT01687114` - Urinary Proanthocyanidin-A2 as a Biomarker of Compliance to Intake of Cranberry Products	N/A
Completed	`NCT02357758` - Effects of Antibiotic Prophylaxis on Recurrent UTI in Children	Phase 4
Completed	`NCT01391793` - Corticosteroids for Children With Febrile Urinary Tract Infections	Phase 3
Completed	`NCT01219595` - Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women	N/A
Completed	`NCT00365430` - SAFE or SORRY? Patient Safety Study of the Prevention of Adverse Patient Outcomes	N/A
Recruiting	`NCT04502095` - Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy	Phase 4
Completed	`NCT00976963` - Single Dose Monurol for Treatment of Acute Cystitis	N/A
Recruiting	`NCT02568800` - Prolonged Infusion Cefepime and Nosocomial Infections	Phase 3
Completed	`NCT02785445` - Healthy.io Method Comparison & User Performance Study	N/A
Completed	`NCT02216253` - L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.	N/A
Completed	`NCT01478620` - Safety and Efficacy of Canephron® N in the Management of Uncomplicated Urinary Tract Infections (uUTI)	Phase 3
Completed	`NCT01054690` - Silver Alloyed Urinary Catheters and Incidence of Catheter Acquired Urinary Tract Infections (UTI)	N/A
Completed	`NCT00371631` - Colonizing Neurogenic Bladders With Benign Flora	Phase 1
Terminated	`NCT03697993` - Safety and Efficacy Study of Oral Fosfomycin Versus Oral Levofloxacin to Treat Complicated Urinary Syndromes (FOCUS)	Phase 4
Terminated	`NCT01803919` - Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients	N/A
Enrolling by invitation	`NCT01231737` - Efficacy of Two Prophylactic Schedules (Prulifloxacin Versus Phosphomycin)	Phase 2
Completed	`NCT01763008` - A Study of the Safety and Effectiveness of Doripenem in Filipino Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections	Phase 4