Urinary Tract Infection Clinical Trial
Official title:
An Open-label, Non-randomized, Multicenter, Interventional Study to Investigate the Safety and Efficacy of Canephron® N in the Management of Uncomplicated Urinary Tract Infections (uUTI)
The objective of the study is to assess safety and impact of a non-antibiotic therapy approach with Canephron® N in the management strategy of uncomplicated lower urinary tract infections (UTIs).
250 patients total 7-day treatment period with Canephron® N (2 tablets three times a day) and
a follow-up period until Day 37. A total of three visits are planned on Day 0 (screening,
start of study treatment), Day 7 (end of study treatment) and Day 37 (end of study visit).
Additional visits can be performed anytime between Day 1 and Day 37 if deemed necessary by
the investigator. In case the patients experience consistent or worsening of symptoms they
may be offered antibiotic therapy at the discretion of the investigator at any time. In this
case Canephron® N intake will be stopped.
At least 50% of the patients, i.e. 125 subjects, should have received a 7-day treatment with
Canephron® N. If less subjects are available recruitment of subjects will be continued until
the required number of 125 subjects is reached.
Due to withdrawal of study in Russia total study population was reduced to 125 patients.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03235947 -
Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients
|
Phase 4 | |
| Terminated |
NCT02198833 -
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection
|
N/A | |
| Withdrawn |
NCT01881165 -
Cranberry on Urinary Tract Infections
|
Phase 4 | |
| Completed |
NCT01687114 -
Urinary Proanthocyanidin-A2 as a Biomarker of Compliance to Intake of Cranberry Products
|
N/A | |
| Completed |
NCT02357758 -
Effects of Antibiotic Prophylaxis on Recurrent UTI in Children
|
Phase 4 | |
| Completed |
NCT01391793 -
Corticosteroids for Children With Febrile Urinary Tract Infections
|
Phase 3 | |
| Completed |
NCT01219595 -
Cranberry Proanthocyanidins for Modification of Intestinal E. Coli Flora and Prevention of Urinary Tract Infections in UTI-Susceptible Women
|
N/A | |
| Completed |
NCT00365430 -
SAFE or SORRY? Patient Safety Study of the Prevention of Adverse Patient Outcomes
|
N/A | |
| Recruiting |
NCT04502095 -
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy
|
Phase 4 | |
| Completed |
NCT00976963 -
Single Dose Monurol for Treatment of Acute Cystitis
|
N/A | |
| Recruiting |
NCT02568800 -
Prolonged Infusion Cefepime and Nosocomial Infections
|
Phase 3 | |
| Completed |
NCT02785445 -
Healthy.io Method Comparison & User Performance Study
|
N/A | |
| Completed |
NCT02216253 -
L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
|
N/A | |
| Completed |
NCT01054690 -
Silver Alloyed Urinary Catheters and Incidence of Catheter Acquired Urinary Tract Infections (UTI)
|
N/A | |
| Completed |
NCT00371631 -
Colonizing Neurogenic Bladders With Benign Flora
|
Phase 1 | |
| Terminated |
NCT03697993 -
Safety and Efficacy Study of Oral Fosfomycin Versus Oral Levofloxacin to Treat Complicated Urinary Syndromes (FOCUS)
|
Phase 4 | |
| Terminated |
NCT01803919 -
Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients
|
N/A | |
| Enrolling by invitation |
NCT01231737 -
Efficacy of Two Prophylactic Schedules (Prulifloxacin Versus Phosphomycin)
|
Phase 2 | |
| Completed |
NCT01763008 -
A Study of the Safety and Effectiveness of Doripenem in Filipino Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections
|
Phase 4 | |
| Completed |
NCT00528476 -
Risk Factors for Recurrent Urinary Tract Infection in Children
|
N/A |