Urinary Tract Infection Clinical Trial
Official title:
Efficacy of Prulifloxacin vs Phosphomycin in the Prophylasy of Urinary Tract Infection
Epidemiological studies showed that 20-30% of patients with uncomplicated urinary tract
infections risked recurrent infection. Urinary tract infection causes marked discomfort for
the patient, has a negative impact upon quality of life, and is associated with high social
and health costs in terms of specialist appointments, laboratory and instrumental tests and
prescriptions . Although diverse cycles of antibiotic therapy and prophylaxis have been
proposed, doubts persist about the most efficacious pharmacological agents, duration of
prophylaxis , the incidence of adverse effects and relapse when antibiotic therapy is
suspended.
Aims of the study:
1. To compare the efficacy of two prophylactic schedules (Prulifloxacin vs Phosphomycin):
- in reducing the number of urinary tract infection episodes during prophylaxis
- in reducing the number of urinary tract infection episodes after prophylaxis
- in improving the patient's quality of life .
2. To assess :
- Tolerability of antibiotic prophylaxis
- The incidence of resistance to antibiotic therapy
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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