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Urinary Incontinence, Stress clinical trials

View clinical trials related to Urinary Incontinence, Stress.

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NCT ID: NCT02400034 Completed - Clinical trials for Stress Urinary Incontinence

Comparing Voiding Trials After Midurethral Sling for Stress Incontinence

Start date: March 2015
Phase: N/A
Study type: Interventional

Urinary incontinence is a prevalent health and quality of life concern affecting almost half of women over the age of 20. Urinary retention (abnormal holding of urine) is a concern of many surgeons who perform midurethral sling surgery. All patients after outpatient midurethral sling or vaginal prolpase surgery must complete a voiding trial if they are to be discharged without a catheter. The purpose of this study is to compare two different types of postoperative voiding trials to determine which leads to less post-operative issues, such as urinary retention requiring catheterization. You are being asked to participate because you are having midurethral sling surgery, either with or without vaginal prolapse repair.

NCT ID: NCT02348112 Completed - Clinical trials for Stress Urinary Incontinence

Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence

Start date: January 2015
Phase:
Study type: Observational

The aim of this postmarket study is to compare the safety and effectiveness of the Altis Single Incision Sling (SIS) to an FDA cleared transobturator and/or retropubic sling through 36 months.

NCT ID: NCT02337374 Completed - Clinical trials for Urinary Incontinence, Stress

Predictive Role of Urodynamics on Mid-urethral Sling Failure

UPMUSF
Start date: June 2010
Phase: N/A
Study type: Observational

Purpose The aim of this study is to investigate the contribution of preoperative urodynamics to mid-urethral slings (MUS) success for developing an algorithm that uses conventional and easily accessible tools Methods Women with stress urinary incontinence and who desired surgical correction of their incontinence were included in the study. The selection of the procedure was according to an algorithm used in an institution developed by a chief of urogynecology department who had 25 years of urogynecology experience. Urodynamic and baseline factors that may be associated with surgery failure were analyzed in MUS failure.

NCT ID: NCT02334878 Completed - Clinical trials for Urinary Incontinence, Stress

Stem Cell Therapy for Treatment of Female Stress Urinary Incontinence

Start date: October 1, 2015
Phase: Phase 3
Study type: Interventional

This study evaluates the effectiveness of mesenchymal stem cells in treatment of stress urinary incontinence due to intrinsic sphincter deficiency; in which the problem is weakness or damage of the sphincter muscle responsible for continence. Mesenchymal stem cells are undifferentiated cells which can undergo self-renewal & differentiation into other cell types like muscle cells; thus can be used to regenerate the damaged sphincter muscles. In this study mesenchymal stem cells will be obtained from bone marrow from the patient, processed, & then re-injected periurethrally. Effectiveness will be compared to that of the surgical treatment (tension-free vaginal tape).

NCT ID: NCT02319096 Completed - Clinical trials for Urinary Stress Incontinence

Vibration Training and Pelvic Floor Muscle Strength in Females With Stress Urinary Incontinence

Start date: December 2014
Phase: N/A
Study type: Interventional

Pelvic floor muscle training (PFMT) is the first line therapy recommended by NICE for the treatment of SUI. Due to poor motivation and compliance only 15-20% of women comply with the regimen. Whole body vibration (WBV) exercise has been developed as a new modality in the field of physiotherapy. The Galileo machine is a unique device for applying whole-body vibration. The investigators are currently using this therapy as an alternative to traditional pelvic floor muscle therapy. The investigators aim to audit the investigators treatment of whole body vibration.

NCT ID: NCT02296099 Completed - Clinical trials for Urinary Incontinence, Stress

Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence

Start date: November 2014
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine if the administration of liposomal bupivacaine at the completion of a suburethral sling procedure will result in decreased postoperative pain compared to no injection.

NCT ID: NCT02291432 Completed - Stress Clinical Trials

Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery

Start date: February 19, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

To study the safety and potential efficacy of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) for the treatment of male stress urinary incontinence (SUI) for patients that have undergone prior prostate surgery.

NCT ID: NCT02288455 Completed - Clinical trials for Male Stress Urinary Incontinence

Clinical Investigation of GT UrologIcal, LLC's Artificial Urinary Sphincter (RELIEF II)

RELIEFII
Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this investigation is to demonstrate the safety and efficacy of the GTU artificial urinary sphincter device in restoring continence in males who have confirmed urinary stress incontinence for a minimum of 12 months with primary etiology being radical prostatectomy or transurethral resection of the prostate (TURP).

NCT ID: NCT02263534 Completed - Clinical trials for Stress Urinary Incontinence

Comparing Minisling to Tension Free Vaginal Tape in Mangement of Stress Urinary Incontinence

Start date: November 10, 2014
Phase: Phase 2/Phase 3
Study type: Interventional

Based on previous studies the single incision minisling is an easy less invasive procedure with fewer complications and cure rate similar to conventional midurethral slings in the treatment of female stress urinary incontinence. The aim of this study is to test the hypothesis that the single incision mini-sling placed in the "U" position is not inferior to TVT in this patient population.

NCT ID: NCT02214784 Completed - Clinical trials for Stress Urinary Incontinence

Neurotech Vital Device For The Treatment Of Stress Urinary Incontinence

Start date: December 2012
Phase: N/A
Study type: Interventional

Stress Urinary Incontinence (SUI) is described as an uncontrolled loss of urine which happens when physical activities such as running, jumping and lifting etc are carried out or when increased pressure to the bladder in everyday life is applied by simply sneezing or coughing. There are various treatment options available - surgical operations, pelvic floor exercises/muscle training and electrical stimulation. This study aims to prove that using the Neurotech Vital device for 12 weeks can stimulate the pelvic floor muscles to strengthen and tone them and in doing so improving stress urinary incontinence. We are comparing the Neurotech Vital device with an altered Neurotech Vital device that does not give the same stimulation treatment. There is a 50% chance of you receiving the altered device, if you do, you will be offered the non-altered Neurotech vital device after your first 12 week treatment programme. Both devices are identical in looks, but give different stimulations through the skin contact electrodes.