Functional Outcome of Urethral Reconstructive Surgery

Status Completed

Clinical Trial Summary

The analysis of the long-term outcomes and quality-of-life parameters after urethral reconstruction surgery.

Clinical Trial Description

Urethroplasty is the surgical repair of a urethral stricture. Depending on the location, severity and length of the stricture, various techniques can be performed.

The first procedure consists of the excision of the stenotic segment and end-to-end anastomosis. Other procedures consist of widening the urethra with buccal mucosa as free graft or with vascularized (genital) skin flaps. The results of these techniques have been described in prospective cohort studies, but to date there is little good data about the functional outcome and quality-of-life with longer follow-up after this surgery.

The purpose of this study is to prospectively follow patients for functional outcome parameters and quality-of-life to obtain long-term information concerning these surgeries. ;

Study Design

Related Conditions & MeSH terms

Urethral Stricture

Clinical Trial Details

NCT number	NCT01982136
Study type	Observational [Patient Registry]
Source	Universitaire Ziekenhuizen Leuven
Contact
Status	Completed
Phase
Start date	August 2009
Completion date	October 2019

View Details

See also
Status	Clinical Trial	Phase
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Recruiting	`NCT05519566` - The Accuracy of Pulsed Fluoroscopy Retrograde Urethrogram Vs the Traditional Retrograde Urethrogram In Diagnosing Urethral Stricture	N/A
Recruiting	`NCT04071925` - 9000 URETHRA STUDY: a Study About Urethroplasty for Urethral Stricture Disease
Terminated	`NCT02551783` - Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft	N/A
Active, not recruiting	`NCT03270384` - Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease	N/A
Completed	`NCT03973619` - Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty	N/A
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Not yet recruiting	`NCT03258658` - Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures	Phase 1
Not yet recruiting	`NCT06384066` - Mobile Health Application to Improve Patient Satisfaction After Urethroplasty	N/A
Completed	`NCT03859024` - Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty	Phase 4
Not yet recruiting	`NCT06064968` - Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral Stricture	N/A
Active, not recruiting	`NCT03499964` - ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease	N/A
Terminated	`NCT02634619` - A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty	N/A
Not yet recruiting	`NCT00918528` - Effect of Mitomycin C on Urethral Stricture Recurrence After Internal Urethrotomy	Phase 1/Phase 2
Completed	`NCT05078788` - Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture	N/A
Enrolling by invitation	`NCT03205670` - Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers	Early Phase 1