Clinical Trials Logo

Clinical Trial Summary

The goal of this clinical trial is to test if metoclopramide can improve effectiveness of endoscopic intervention in upper gastrointestinal (GI) bleeds. The main questions the investigators hope to answer is Does metoclopramide lessen the need for repeat endoscopy, interventional radiology intervention or surgery in cases of upper GI bleed? Does metoclopramide improve visibility of the GI walls in cases of upper GI bleed?


Clinical Trial Description

The purpose of the study is to see if giving metoclopramide prior to an endoscopy in cases of upper GI bleed can decrease the need for repeat endoscopy due to poor visibility. Metoclopramide stimulates stomach and intestine activity. It is used to treat nausea, vomiting and slow gut movement. The investigators are testing if metoclopramide's effect on stimulating stomach activity can lead to more effective emptying of blood from the stomach and upper intestines in upper GI bleeding so physicians conducting endoscopies can easily see the stomach and intestinal wall and treat the source of bleeding. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05746377
Study type Interventional
Source Mercy Health System
Contact Mudassar K Sandozi, DO
Phone (815) 971-2544
Email msandozi@mhemail.org
Status Recruiting
Phase Phase 4
Start date May 20, 2023
Completion date June 2024

See also
  Status Clinical Trial Phase
Terminated NCT01448382 - Evaluation of PillCam With Blood-Sensing Feature: A Feasibility Study Phase 1
Recruiting NCT06167837 - Metoclopramide for Gastric Visualization in Active Upper GI Bleeding Phase 4
Recruiting NCT05582174 - PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers Phase 4
Not yet recruiting NCT06254352 - Clinical Risk Scores in Prediction Outcome of Acute UGIT Bleeding in Non Cirrhotic Patients
Recruiting NCT05415124 - Presence or Absence of Blood in the GI Lumen N/A
Recruiting NCT05474937 - Inhalation of Sevoflurane Versus Intravenous Midazolam,Ketamine,Propofol For Pediatrics Undergoing Upper GI Endoscopy N/A
Recruiting NCT05457062 - Analysis the Vocs in Upper GI Bleeding Patients
Recruiting NCT05876741 - Validation of Prognostic Accuracy of ABC ( Age, Blood Urea Nitrogen , Co-morbidities ) and Horibe Pre-endoscopy Scoring Systems in Patients With Upper Gastrointestinal Bleeding in Sohag University Hospital .
Recruiting NCT05763745 - Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy: a Pilot Study N/A
Completed NCT03176407 - Detection of Upper Gastrointestinal (GI) Bleeding With a Novel Bleeding Sensor Capsule [DING] N/A