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Clinical Trial Summary

This will be a prospective observational study where the investigator will scan patients' necks with an ultrasound and look for anatomical landmarks that may help identify the phrenic nerve.


Clinical Trial Description

Patients under protective mechanical ventilation, an intervention that saves lives, may need sedation and paralyzing agents. However, sedation and paralyzing agents are associated with multiple complications, including diaphragm dysfunction. Several strategies have been proposed to reduce diaphram dysfunction. A novel approach is to stimulate the phrenic nerve, either transvenously or transcutaneously. Transvenous stimulation requires a catheter, which eventually is associated with increased risk of infection and thrombosis. In this scenario, transcutaneous phrenic nerve pacing is attractive but may be more susceptible to patients' anthropometric measures. The correlation between patients' anthropometric measures and the location of the phrenic has been poorly studied. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05875883
Study type Observational
Source Unity Health Toronto
Contact Laurent Brochard, MD
Phone 416-864-6060
Email Laurent.Brochard@unityhealth.to
Status Not yet recruiting
Phase
Start date August 7, 2023
Completion date December 4, 2023

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