Evaluating the Endometrial Receptivity of FET Patient by Ultrasounicelastography

Ultrasonography Clinical Trial

Official title:

Evaluating the Endometrial Receptivity of FET Patients by Ultrasounicelastography and Predicting the Pregnancy Outcome.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03881072
• Other study ID #: UE evaluating Em-receptivity
• Status: Completed
• Phase: N/A
• Start date: October 1, 2017
• Est. completion date: December 10, 2018

Study information

• Verified date: March 2019
• Source: Jinling Hospital, China
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Prospective clinical study ：observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Description:

Randomly selecting 20-40 years patients were prepared to accept frozen embryo transplant ; HRT cycle preparation of endometrium；choosing HRT plan to prepare the transplantation endometrium.Establishing a strict standard of exclusion and exclude standard to exclude endometrial lesions and underlying disease.The patients were given elastography for 5-7 days afterEndometrium transformation.Observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: December 10, 2018
• Est. primary completion date: January 10, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

1. the volunteers voluntarily signed the informed consent.

2. female patients between 20-40 years old.

3. HRT cycle.

4. no uterine cavity operation was performed within 3 months.

Exclusion Criteria:

1. endometrial polyps, abnormal uterine cavity, intrauterine adhesions and dysplasia of uterus.

2. hydrosalpinx was not ligated.

3. patients with uterine myoma and uterine fibroids;

Related Conditions & MeSH terms

• Assisted Reproductive Technology
• Ultrasonography

Intervention

Other:
• Ultrasounicelastography
Observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate.

Locations

Country	Name	City	State
China	Yao Bing	Nanjing	Jiang Su

Sponsors (1)

Lead Sponsor	Collaborator
Jinling Hospital, China

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	endometrial receptivity	Observing the correlation between elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate.	Month 12