Ulcerative Colitis Clinical Trial
Official title:
Mucosal and Systemic Immune Modulation From Trichuris Suis in a Self-infected Individual
Verified date | March 2017 |
Source | University of Aarhus |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Mucosal immunology during helminth infection
Status | Completed |
Enrollment | 1 |
Est. completion date | December 31, 2012 |
Est. primary completion date | December 31, 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - The included volunteer is a researcher within parasitology with main focus on Trichuris trichiura and Trichiura suis. He planned to infect himself and contacted our department with the purpose of being monitored during this infection for safety (medical supervision) and research reasons. The only clinical criterion for his inclusion in the study was that he was healthy. Exclusion Criteria: |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University of Aarhus |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Faecal egg excretion | Weekly monitoring of fecal egg counts by microscopy | 15 weeks | |
Secondary | Mucosal T cell associated cytokines | Biopsy sampling during established infection | 15 weeks | |
Secondary | Systemic immune parameters (eosinophilia, Subtypes of circulating T cells) | Blood samples every week | 15 weeks | |
Secondary | Adverse events | Clinical evaluation every week | 15 weeks |
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