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NCT01282905 Clinical Trial

Hydrogen Sulfide Detoxification and Butyrate Metabolism in Ulcerative Colitis

Ulcerative Colitis Clinical Trial

Official title:
Impact of the Mucosal Detoxification Mechanism of Hydrogen Sulphide on the Oxidation Pathway of Butyrate in Ulcerative Colitis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01282905
Other study ID # ML3999
Secondary ID
Status Completed
Phase N/A
First received January 24, 2011
Last updated January 25, 2011
Start date October 2008
Est. completion date December 2010

Study information
Verified date January 2011
Source Katholieke Universiteit Leuven
Contact n/a
Is FDA regulated No
Health authority Belgium: Ethics Committee
Study type Observational

Clinical Trial Summary

The purpose of this study is to evaluate the relation between sulphide detoxification and butyrate metabolism at the level of gene expression and enzyme activity in ulcerative colitis patients and healthy controls.

Recruitment information / eligibility
Status Completed
Enrollment 106
Est. completion date December 2010
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Ulcerative colitis patients: patients diagnosed with ulcerative colitis

Exclusion Criteria:

- Healthy controls: no diagnosis of inflammatory bowel diseases

- Intake of antibiotics in the last month before the study

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Belgium KULeuven Leuven

Sponsors (1)
Lead Sponsor Collaborator
Katholieke Universiteit Leuven

Country where clinical trial is conducted

Belgium, 

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