Ulcerative Colitis Clinical Trial
Official title:
Randomised,Controlled Trial of Narrow Band Imaging With Magnification (NBI) Versus White Light Endoscopy for Dysplasia Detection in Ulcerative Colitis Surveillance
The purpose of the study is to determine whether a new colonoscopic viewing technique called narrow band imaging (NBI) helps doctors detect more patients with at leat one pre-cancerous area (dysplasia associated lession or mass, MALMs) than conventional colonoscopy using white light alone.
Status | Recruiting |
Enrollment | 110 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - petients with colitis who meet surveillance criteria - patients over 18 years of age Exclusion Criteria: - pregnant patients - unable or unwilling to give informed consent - patients with severe active colitis who would be unsafe to endoscope |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
United Kingdom | North West London Hospitals NHS Trust - St Mark's | London | Middlesex |
United Kingdom | Nottingham Univesrity Hospitals NHS Trust, Queen's Medical Centre | Nottingham |
Lead Sponsor | Collaborator |
---|---|
London North West Healthcare NHS Trust | Nottingham University Hospitals NHS Trust |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Effectiveness of NBI versus Light endoscopy | |||
Secondary | Are more precancerous lessions found in total with NBI? | |||
Secondary | Are more advanced precancerous lesions found with NBI? | |||
Secondary | Are more patients found with more that one precancerous lesion with NBI? | |||
Secondary | How Many lessions are successfully completely removed via the endoscope? |
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