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Ulcerative Colitis Exacerbation clinical trials

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NCT ID: NCT03441893 Active, not recruiting - Ulcerative Colitis Clinical Trials

Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis

Start date: January 1, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract of unknown etiology. UC is characterized by recurring episodes of inflammation limited to mucosal and submucosal layers of the colon. The object of the present study was to determine the prevalence of intestinal protozoa and helminthes in UC patients, and the role of this changes in aetiopathogenesis of diseases. Patients will be examined before and after therapy. Parasites and protozoa prevalence and intensity will be detected by triple coproscopy.Microbiological study will be conducted before therapy for detection pathogenic bacteria only from UC patients infected with B. hominis . If intestinal pathogenic bacteria are found, participants will be excluded from further investigation.