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Ulcer clinical trials

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NCT ID: NCT05772507 Recruiting - Diabetic Foot Ulcer Clinical Trials

Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION)

Start date: August 22, 2023
Phase: N/A
Study type: Interventional

Evaluation of the efficacy (wound epithelialization and time to closure) and tolerance (emergence and nature of adverse event) of the new URGO AWC_008 and URGO AWC_022 dressings in local management of acute and chronic wounds at risk of local infection or with clinical signs of local infection

NCT ID: NCT05771155 Not yet recruiting - Ulcerative Colitis Clinical Trials

Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio®

UCESIVE
Start date: May 2023
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, parallel arm, double-blind study with approximately 750 participants with moderately to severely active Colitis Ulcerosa randomized to receive either PB016 or Entyvio®

NCT ID: NCT05770609 Recruiting - Clinical trials for Mild to Moderate Ulcerative Colitis

A Study of SPH3127 in the Treatment of Mild to Moderate Ulcerative Colitis

Start date: June 19, 2023
Phase: Phase 2
Study type: Interventional

To preliminarily evaluate the clinical efficacy of the renin inhibitor SPH3127 Tablets in patients with mild to moderate ulcerative colitis with placebo as a control and determine the recommended dose.

NCT ID: NCT05767320 Not yet recruiting - Clinical trials for Perforated Peptic Ulcer

Open vs Laparoscopic Repair of Perforated Peptic Ulcer

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

comparison between outcomes of both open and laparoscopic repair of perforated peptic ulcer

NCT ID: NCT05767021 Recruiting - Ulcerative Colitis Clinical Trials

A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis

LUCENT-URGE
Start date: May 17, 2023
Phase: Phase 3
Study type: Interventional

A study to investigate bowel urgency in adults with moderately to severely active ulcerative colitis (UC) treated with mirikizumab. The study will have 4 periods and will last for 36 weeks.

NCT ID: NCT05764876 Active, not recruiting - Yaws Clinical Trials

Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws)

Trep-AByaws
Start date: March 14, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to test the non inferiority of linezolid compared with azithromycin as a treatment for yaws . The main questions it aims to answer are: can linezolid cure active yaws, and can linezolid cure latent yaws. Participants with serologically confirmed yaws will be randomized to receive linezolid (experimental) or azithromycin (control group) treatment and followed up to assess clinical resolution.

NCT ID: NCT05763654 Recruiting - Pressure Ulcer Clinical Trials

PMCF Study on the Safety of Linovera Emulsion for the Prevention of Cat-1 Pressure Ulcers, Vascular and DFU

PRELINEM
Start date: December 15, 2022
Phase:
Study type: Observational [Patient Registry]

To assess the safety of Linovera® Emulsion in the prevention of Grade I Pressure ulcers, Vascular and Diabetic Foot Ulcers. To assess the performance of Linovera® Emulsion for the prevention of stage 1 Pressure Ulcers, Vascular and Diabetic Foot Ulcers.

NCT ID: NCT05762432 Not yet recruiting - Diabetic Foot Ulcer Clinical Trials

Diabetic Foot Ulcer Research Study

Start date: February 26, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare safety and performance of the study device to the current typical NHS standards of care device. The main outcomes it aims to achieve are: Complete wound healing at 12 weeks (100% epithelialised) % Reduction in wound area at 12 weeks Participants will attend their NHS podiatry clinic appointment as normal and will be assigned either the study device or the current typical NHS standard of care device. Researchers will compare the study device group to the standard group to assess the outcomes mentioned previously.

NCT ID: NCT05761327 Completed - Ulcerative Colitis Clinical Trials

Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis

Start date: June 3, 2022
Phase: N/A
Study type: Interventional

The aim of the study was to examine and compare the effects of Mediterranean diet, curcumin supplementation with Mediterranean diet in individuals with ulcerative colitis, and resveratrol supplementation with Mediterranean diet in individuals with ulcerative colitis, on disease symptoms, quality of life, and inflammatory biomarkers.

NCT ID: NCT05758545 Recruiting - Diabetic Foot Ulcer Clinical Trials

Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers

Mavericks
Start date: June 19, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs). The prospective randomized, double-blinded, sham-controlled trial is designed to demonstrate superiority of wound closure of the COMS One device to a sham-control device at 12 weeks post-application, when each is administered in conjunction with standard of care (SOC) in the treatment of DFUs.