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Ulcer clinical trials

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NCT ID: NCT00333749 Completed - Oral Ulcer Clinical Trials

The Effectiveness of Pasteurized Goat Milk in the Treatment of Childhood Oral Ulcer Diseases

Start date: January 2006
Phase: Phase 1
Study type: Interventional

Children with acute diseases with oral ulcers (not included PRESENTATIONS OF SLE, IBD or IMMUNOCOMPRMIZED STATES)will receive several doses (drinking or mouth rinsing) of either pasteurized goat milk or cow milk. Children will than be followed for length of the disease - signs and symptoms.

NCT ID: NCT00326209 Completed - Ulcerative Colitis Clinical Trials

Long-Term Safety and Tolerability of Mesalamine Pellets in Participants With Ulcerative Colitis in Remission

Start date: December 22, 2005
Phase: Phase 3
Study type: Interventional

To evaluate the long-term safety and tolerability of encapsulated mesalamine Granules (eMG) (formerly referred to as Mesalamine Pellets [MP]) in participants with ulcerative colitis currently in remission.

NCT ID: NCT00324168 Completed - Corneal Ulcer Clinical Trials

Steroids for Corneal Ulcers Trial

SCUT
Start date: September 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether adding topical steroids improves the outcomes of bacterial corneal ulcers, especially visual acuity.

NCT ID: NCT00319696 Completed - Digital Ulcers Clinical Trials

Bosentan in Digital Ulcers

RAPIDS 2 OL
Start date: July 8, 2004
Phase: Phase 3
Study type: Interventional

The aim of the study is to collect long-term efficacy, tolerability and safety data of bosentan in Systemic Sclerosis (SSc) patients suffering from ischemic digital ulcers (DUs).

NCT ID: NCT00312364 Completed - Clinical trials for Diabetes Complications

Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers

Start date: December 2005
Phase: Phase 2
Study type: Interventional

This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers. Patients participating in the study may receive an active drug (MRE0094), inactive drug (placebo), or a gel used to treat diabetic foot ulcers currently available for sale in the United States. What treatment a patient will receive is determined by chance (like drawing a number from a hat). All patients will receive additional care for diabetic foot ulcers during the study. Participation in the study can be up to 4½ months.

NCT ID: NCT00303381 Completed - Ulcerative Colitis Clinical Trials

Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis

Start date: December 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of interferon-beta-1a in subjects with active ulcerative colitis (UC).

NCT ID: NCT00301496 Completed - Venous Ulcer Clinical Trials

Randomized Controlled 8-Week Crossover Evaluation of Compression Bandage Systems for Venous Leg Ulcers

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the product performance of a new 2-layer compression bandage for the treatment of venous leg ulcers.

NCT ID: NCT00299013 Completed - Ulcerative Colitis Clinical Trials

Study of COLAL-PRED® in the Treatment of Moderate Acute Ulcerative Colitis

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether a novel dosage form of a prednisolone ester, called COLAL-PRED®, is useful in the treatment of ulcerative colitis.

NCT ID: NCT00295282 Completed - Ulcerative Colitis Clinical Trials

A Dose-Escalation Study of MDX-1100 in Patients With Active Ulcerative Colitis

Start date: January 2006
Phase: Phase 1
Study type: Interventional

This is a Phase I dose-escalation study of MDX-1100. patients with ulcerative colitis will be enrolled into one of four dose cohorts, to receive of MDX-1100 at 0.3, 1.0, 3.0 or 10mg/kg. Three to six patients will be enrolled at each dose level, starting at the lowest dose level, for a maximum of 24 patients to be enrolled into the study. The study is designed to establish the safety and tolerability of single doses of MDX-1100 administered in dose-escalating cohorts to patients with ulcerative colitis. Other study objectives include characterizing a pharmacokinetic profile and pharmacodynamic effects of MDX-1100 and determination of immunogenic response to MDX-1100.

NCT ID: NCT00288392 Completed - Foot Ulcer Clinical Trials

Efficacy of Soluble Beta-1,3/1,6-Glucan Compared to Placebo on Chronic Leg Ulcers in Diabetes Patients

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of soluble beta-1,3/1,6-glucan compared to placebo on the healing of chronic leg ulcers in diabetes patients. Hypothesis: Through its ability to activate tissue macrophages and counteract diabetes-associated defects in macrophages, the soluble beta-1,3/1,6-glucan will promote the healing of leg ulcers in diabetic patients.