Effects of Eccentric Training on Glycemic Control and Quality of Life in Patients With Type II Diabetes Mellitus

Type II Diabetes Mellitus Clinical Trial

Official title:

Effects of Eccentric Training on Glycemic Control and Quality of Life in Patients With Type II Diabetes Mellitus

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06387550
• Other study ID #: FUI/CTR/2024/3
• Status: Recruiting
• Phase: N/A
• Start date: March 20, 2024
• Est. completion date: July 15, 2024

Study information

• Verified date: April 2024
• Source: Foundation University Islamabad
• Contact: Hajab Zehra, MS-MSKPT*
• Phone: +923165089308
• Email: hajabzehra765[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Diabetes is defined by the level of hyperglycemia its a metabolic chronic disorder that furthur lead to life threatning medical conditions however, the prevalence of diabetes is rapidly increasing day by day in both developed and developing countries making it global pandemic and type II is more prevalent. Life dependency is increased due to long term effects of diabetes in specifically older individuals. Physical activity and exercise improves glucose tolerance and also reduces other life threatening diabetic complications, improving the quality of life in diabetic population.

Description:

Diabetes is a metabolic chronic disorder and its becoming a global pandemic and its prevalence rises quickly in both developed and developing countries.Diabetes confirmation is done through levels of hyperglycemia. According to American Diabetic Association level of HBA1C is greater than 6.4

% indicate presence of diabetes.Type II is more prevalent and its deteriorting effect on body with increasing age are more pronounced.Insuline resistance and impaired glucose tolerance are seen in type II diabetes mellitus patients.

Studies depict that regular exercise improve glycemic control and improve insuline sensitivity and enhance glucose uptake by muscles.

Strength training enhance quality of life and protect your joints from injury. Previous studies have specified the impact of several types of training on older adults, young healthy adults and diabetic patients but there is limited literature found in terms of solely observing the effect of eccentric training on glycemic control and quality of life in diabetic patient.

Current study was designed to determine the effects of eccentric training on glycemic control and quality of life in type II diabetes Mellitus.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: July 15, 2024
• Est. primary completion date: July 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

• Both gender

• Blood pressure should be <140/90mm of Hg

• Diagnosed Diabetic patient (HBA1C>6.4%)

• Adults (Age 40 +) from Rawalpindi and Islamabad

Exclusion Criteria:

• Acute infection

• History of recent trauma

• Acute coronary syndrome

• Peripheral vascular diseases

Related Conditions & MeSH terms

• Diabetes Mellitus
• Diabetes Mellitus, Type 2
• Type II Diabetes Mellitus

Intervention

Procedure:
• Eccentric Training
Warm up phase that include hip circles and shoulder rolls(1 sets of 5 reps), participants are trained on bicycle ergometer for 15 minutes on 2-3 times a week and its duration is increased according to patient tolerance, after that they will be pass through exercise phase that include squating, lunges and leg press (8-10 reps of 3 sets) after that cool down phase begin that include cat cow stretch and oblique stretch (5 reps of 1 set)

Locations

Country	Name	City	State
Pakistan	Foundation University College of Physical Therapy	Rawalpindi	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Foundation University Islamabad

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Glycemic control	Lab investigation of glycemic control will be through HBA1C test.	8 weeks
Primary	Patient's quality of life	Quality of life will be assessed using EQ5DL Questionnaire.	8 weeks