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NCT01961024 Clinical Trial

Postprandial VLDL-TG Metabolism

Type 2 Diabetes Clinical Trial

Official title:
Postprandial VLDL-TG Metabolism

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01961024
Other study ID # ES-0006
Secondary ID
Status Completed
Phase N/A
First received September 27, 2013
Last updated May 1, 2017
Start date January 2014
Est. completion date August 2015

Study information
Verified date May 2017
Source University of Aarhus
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.

Recruitment information / eligibility
Status Completed
Enrollment 21
Est. completion date August 2015
Est. primary completion date August 2015
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Male
Age group 30 Years to 70 Years
Eligibility Inclusion Criteria:

- Written consent

Exclusion Criteria:

- Known diseases

- Alcohol abuse

- Smoker

- Regular use of medicine

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Denmark Department of Endocrinology MEA, Aarhus Hospital Aarhus C Please Select

Sponsors (1)
Lead Sponsor Collaborator
University of Aarhus

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Primary VLDL-TG storage in adipose tissue 3 hours
Secondary 18F-THA fractional storage 6 Hours
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