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Turner Syndrome clinical trials

View clinical trials related to Turner Syndrome.

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NCT ID: NCT03274973 Terminated - Growth Disorders Clinical Trials

Study to Assess Long-term Effectiveness of Zomacton® and Treatment Adherence in Patients With Growth Hormone Deficiency or Ullrich-Turner Syndrome

RAZANT
Start date: May 14, 2018
Phase:
Study type: Observational

Assessment of long-term effectiveness of ZOMACTON in treatment of Growth Hormone Deficiency or growth retardation due to Ullrich-Turner Syndrome and assessment of compliance and adherence, optionally with the aid of an electronic app or patient diary.

NCT ID: NCT02496598 Terminated - Infertility Clinical Trials

In Vitro Follicle Activation

IVA
Start date: July 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of an experimental treatment, known as in vitro activation (IVA) of dormant ovarian follicles, for infertility in women diagnosed with primary ovarian insufficiency (POI).

NCT ID: NCT02226315 Terminated - Down Syndrome Clinical Trials

Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies

Start date: August 2014
Phase: N/A
Study type: Observational

This study will evaluate the clinical performance of massively parallel sequencing (MPS) using the MaterniT21 PLUS LDT in the detection of fetal aneuploidy in circulating cfDNA extracted from a maternal blood sample obtained from women pregnant with a multiple gestation who were at increased risk for fetal aneuploidy.

NCT ID: NCT02181595 Terminated - Clinical trials for Ovarian Insufficiency

Deep Reading as a Contemplative Practice for Women With Primary Ovarian Insufficiency

Start date: July 2, 2014
Phase: Phase 1
Study type: Interventional

Background: - Women with Primary Ovarian Insufficiency (POI) have ovaries that stopped working normally before they turned 40. This usually causes infertility, which challenges many women with the condition to ask themselves, Why me? This kind of question is about our human existence, or what some call an existential view of life. Researchers have learned that spirituality and finding existential purpose help women with POI. So does meeting other women with the same problem. Researchers want to find new ways to help women with POI cope with it. Objective: - To develop and test a practice for women with POI called Deep Reading. Eligibility: - Women enrolled in another POI protocol, who can read and speak English. Design: - Participants will first have an individual visit or phone call. They will describe spiritual or existential practices they have done. They will also answer questions about spiritual and existential health and daily functioning. - They will join a group for 6 weekly sessions. Each session will be 60 90 minutes. - In each group session, a coordinator will teach participants about Deep Reading. They will read a piece of up to 1000 words. They will think about the piece and then talk about it with the group. - Between sessions, participants will practice Deep Reading at least once for 15 20 minutes on their own. They will check in once with another group member. They will keep a log of these activities. - After session 3, participants will answer questions online about wellbeing and satisfaction. - At session 6, participants will answer questions online about wellbeing. They will answer questions about their overall experience. - One and 3 months after the sessions end, participants will again complete online wellbeing questionnaires and report on their continued practice of Deep Reading.

NCT ID: NCT02018172 Terminated - Clinical trials for Growth Hormone Deficiency

Evaluation of the Adherence and the Patient Acceptability of Zomacton® Treatment With the Zomajet® Vision X Device

ZOMAXEPT
Start date: July 2014
Phase: N/A
Study type: Observational

The study is performed to collect long-term data on the treatment adherence and patient's acceptability when Zomacton®10 mg is administered with the Zomajet® Vision X device in patients with a growth hormone deficiency or Turner's syndrome.

NCT ID: NCT00870220 Terminated - Turner's Syndrome Clinical Trials

Initiating Transdermal Estradiol Therapy in Turner's Syndrome

Start date: April 2009
Phase: Phase 1
Study type: Interventional

This is a multicenter, randomized, controlled, semi-blinded study to compare two low doses of estradiol administered by recently available transdermal patches for the initiation of puberty in Turner syndrome girls 11.5-13.0 years old in conjunction with growth hormone (GH) therapy. The specific hypotheses to be tested are: when combined with growth hormone (GH) treatment, low dose transdermal estradiol (LTE2) replacement will be more effective in stimulating feminization, height velocity, and bone mineral density without compromising growth potential than very low dose transdermal estradiol (VLTE2), which will in turn be superior to GH alone in effects on feminization, height velocity, and bone mineral density.

NCT ID: NCT00650754 Terminated - Clinical trials for Primary Ovarian Insufficiency

Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility

DHEAFert
Start date: March 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with otherwise unexplained infertility and evidence of premature ovarian aging (POA).

NCT ID: NCT00419107 Terminated - Turner Syndrome Clinical Trials

Beta Cell Function in Women With Turner Syndrome

Start date: November 2004
Phase: N/A
Study type: Observational

Diabetes is more frequent in women with Turner syndrome. The purpose of this study is to see, in what ways the glucose metabolism is different in this study population. The hypothesis is that women with Turner Syndrome have an impaired insulin production (beta cell function).

NCT ID: NCT00121875 Terminated - Turner Syndrome Clinical Trials

Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature

Start date: June 2005
Phase: Phase 4
Study type: Observational

Growth hormone treatment improves body fat distribution but also causes insulin resistance. Scientists have recently linked insulin resistance with special stores of fat in the muscles, which can be measured by magnetic resonance imaging (MRI). The researchers hypothesize that growth hormone will paradoxically reverse the linkage between muscle fat stores and insulin resistance. To assess this association and to investigate the cause(s), the researchers will measure muscle fat stores during growth hormone treatment. Other parameters linked to insulin resistance (glucose tolerance, blood markers, and body composition) will also be assessed. This study may lead to improved strategies for monitoring growth hormone therapy.