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Tumor clinical trials

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NCT ID: NCT06108232 Not yet recruiting - Follicular Lymphoma Clinical Trials

Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma

Start date: March 31, 2024
Phase: Phase 2
Study type: Interventional

To learn if obinutuzumab in combination with CC-99282 can help to control previously untreated, high tumor burden FL

NCT ID: NCT06006845 Recruiting - COVID-19 Clinical Trials

Time to Initiated Antitumor Therapy for Tumor Patients With COVID19 Infection

Start date: December 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to study the safety of initiation of antitumor therapy early after nucleic acid test turn negativity in tumor patients infected with COVID-19. The main questions aims to answer are: - Whether initiation of antitumor therapy early after nucleic acid test turn negativity in tumor patients infected with COVID-19 increases adverse events related to antitumor therapy. - Whether initiation of antitumor therapy early after nucleic acid test turn negativity in tumor patients infected with COVID-19 increases risk of re-infection of COVID-19. - How initiation of antitumor therapy early after nucleic acid test turn negativity in tumor patients infected with COVID-19 affects QoL of tumor patients Participants will be asked to answer the question about: - the severity and duration of COVID-19 symptoms - the date of diagnosis of COVID-19 - the date of negative nucleic acid test - the QoL of life before infection with COVID-19, during infection of COVID-19, after nucleic acid test negativity and receiving antitumor therapy

NCT ID: NCT05997017 Recruiting - Cancer Clinical Trials

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Start date: December 28, 2023
Phase: Phase 2
Study type: Interventional

A Phase 2 Multi-center Open-label Trial of nab-Sirolimus in Combination with Letrozole in Advanced or Recurrent Endometrioid Endometrial Cancer

NCT ID: NCT05879146 Not yet recruiting - Tumor Clinical Trials

Evaluation of the Response and Non-response of Nirogacestat in Desmoid Tumors- Clinical Study

Start date: October 30, 2024
Phase: Phase 2
Study type: Interventional

To learn about the safety and effects of an investigational drug called nirogacestat when given to participants with a desmoid tumor/aggressive fibromatosis

NCT ID: NCT05821920 Recruiting - Clinical trials for Degenerative Disc Disease

A Safety Study on Posterior Pedicle Screw System

MUST MINI PMS
Start date: June 28, 2021
Phase:
Study type: Observational

The goal of this study is to assess the MUST MINI system safety in patient who will undergo a posterior cervical spine fusion intervention. Patients will be invited to partecipate during preoperative visit and follow the postoperative visits according to the standard practice.

NCT ID: NCT05820087 Recruiting - Kidney Cancer Clinical Trials

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)

#HOPE4KIDNEY
Start date: January 4, 2024
Phase: N/A
Study type: Interventional

The purpose of this trial is to evaluate the effectiveness and safety of the HistoSonics Edison System for the destruction of kidney tissue by treating primary solid renal tumors.

NCT ID: NCT05740475 Recruiting - Pulmonary Fibrosis Clinical Trials

A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of 9MW3811 in Healthy Subjects

Start date: March 20, 2023
Phase: Phase 1
Study type: Interventional

This is a first-in-human, single ascending dose study of 9MW3811, the primary objective of which is to evaluate the safety and tolerability of 9MW3811 in healthy adult participants.

NCT ID: NCT05661461 Recruiting - Clinical trials for Advanced Solid Tumor

Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

Start date: November 23, 2022
Phase: Phase 1
Study type: Interventional

This is a phase 1, multi-center, open-label, dose-escalation study of nab-sirolimus in adult patients with locally advanced or metastatic solid tumors and moderate hepatic impairment or normal hepatic function.

NCT ID: NCT05660694 Completed - Tumor Clinical Trials

Comparison of Triamcinolone With Pentoxifylline and Vitamin- E Efficacy in the Treatment of Stage 2 and 3 Oral Submucous Fibrosis

Start date: January 1, 2020
Phase: Phase 4
Study type: Interventional

To compare the efficacy of Triamcinolone with Pentoxifylline and Vitamin E in patients with stage two and three oral submucous fibrosis.

NCT ID: NCT05549557 Not yet recruiting - Tumor Clinical Trials

IMM40H Phase I Dose Escalation and Expansion

Start date: September 2022
Phase: Phase 1
Study type: Interventional

This is first-in-human, open-label, multi-center, dose-escalation (phase Ia) and cohort expansion (phase Ib) phase I study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamic, immunogenicity, and antitumor activities of IMM40H in patients with advanced malignancies including solid tumor and hematological malignancies.