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Tumor Motion clinical trials

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NCT ID: NCT02324530 Recruiting - Breast Cancer Clinical Trials

Evaluation of Continuous Positive Airway Pressure for Tumor Motion Management in Radiotherapy

Start date: December 2013
Phase: Phase 2
Study type: Interventional

This is a clinical study on patients to compare the effects of CPAP on lung volume diaphragm motion, heart position and tumor motion compared to free breathing. Only patients with significant tumor motion of greater than 1 cm amplitude or unfavorable chest wall geometry (heart close to chest wall) identified on standard imaging and simulation will be candidates for the study. Patients will be re- simulated and planned for radiation treatments with CPAP. The radiation plans generated with and without CPAP will be compared to evaluate the impact of CPAP on tumor motion and dose delivered to adjacent critical structures such as the heart and lung.