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Clinical Trial Summary

A Phase 1, Partially Blind, Placebo Controlled, Randomized, Combined Single Ascending Dose with a Food Effect Cohort (Part 1) and Multiple Ascending Dose Study (Part 2) Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TBAJ-876 in Healthy Adult Subjects


Clinical Trial Description

This study is a two-part, partially blinded, placebo controlled, combined single ascending dose (SAD) with food-effect and multiple ascending dose (MAD) study conducted in one study center in the United States. Safety will be assessed throughout the study for all subjects. Safety assessments will include physical examinations, vital signs, serial ECGs, cardiac monitoring, adverse events (AEs), and clinical laboratory tests (including hematology, serum chemistry, coagulation, and urinalysis). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04493671
Study type Interventional
Source Global Alliance for TB Drug Development
Contact
Status Completed
Phase Phase 1
Start date June 8, 2020
Completion date November 15, 2022

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