The Role of Routine Bacterial Culture Including Tuberculosis During Bronchoscopy: A Prospective Study

Tuberculosis Clinical Trial

Official title:

The Role of Routine Bacterial Culture Including Tuberculosis During

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01167647
• Other study ID #: MMC10-087-10.CTIL
• Status: Completed
• Phase: N/A
• First received: July 21, 2010
• Last updated: March 5, 2013
• Start date: July 2010
• Est. completion date: October 2012

Study information

• Verified date: March 2012
• Source: Meir Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Israel:Clalit Health Services
• Study type: Observational

Clinical Trial Summary

Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined.

Description:

Many centers routinely culture bronchoscopy samples for bacteria and mycobacteria even when infections including tuberculosis (TB) are not strongly suspected. However, the value of this practice has been poorly defined. Unnecessary bronchial cultures of bacteria may lead to over treatment in patients without clinical evidence of infections and may increase the drug resistant strains.

In areas with a high prevalence of TB, routine bronchial cultures may detect clinically unsuspected TB in an appreciable proportion of cases. However, in population with a low prevalence of TB, routine culture of bronchial aspirates may incur an unnecessary expanse and may lead to over diagnosis and over treatment of patients with non pathogenic atypical mycobacteria detected by acid-fast bacillus strains.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: October 2012
• Est. primary completion date: October 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. patients who will undergo a bronchoscopy examination at pulmonary department in Meir Medical Center

2. patients who will sign on informed consent. -

Exclusion Criteria:

• 1)age under 18 years

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Tuberculosis

Locations

Country	Name	City	State
Israel	Pulmonary department, Meir Medical Center	Kfar Saba

Sponsors (1)

Lead Sponsor	Collaborator
Meir Medical Center

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	number of positive tuberculosis culture		12 months	No