Tuberculosis Clinical Trial
The broad purpose of this project, proposed by investigators at the University of Alabama at Birmingham and the State of Alabama Department of Public Health, is to use a behaviorally focused education that has been proven effective to enhance the accuracy and efficiency of the contact investigation process. The behaviorally focused intervention will focus on enabling public health workers to understand and implement a recently published model of TB transmission.
BACKGROUND:
Investigation of contacts of patients with active pulmonary tuberculosis (TB) is an
important epidemiological tool in TB control. Unfortunately, due to budgetary and resource
constraints, many health departments struggle to fulfill their responsibility of TB control
through contact investigation.
DESIGN NARRATIVE:
Primary outcome The primary outcome of this project is to examine the clinical effectiveness
of the TB transmission model. This will be done by examining the sensitivity and specificity
of the model when used in a field application.
Key secondary outcomes Evaluation of the efficiency of contact investigation (two outcomes:
1) weekly average time to tuberculin skin test placement for high risk contacts, 2) weekly
average time to the close of the contact investigation.) Qualitative assessment of
individuals who are incorrectly predicted by the model to have a negative tuberculin skin
test
;
N/A
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