Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate the effect of gastrectomy on pharmacokinetic profile of first-line anti-tuberculosis drugs in patients with pulmonary tuberculosis (TB).

Clinical Trial Description

Gastrectomy is a well-known risk factor for TB. Also, there were some reports about malabsorption of anti-TB drugs in the gastrectomized patients. However, pharmacokinetics of recently used first line anti-TB drugs in the gastrectomized patients have not been well evaluated simultaneously. Therefore, the investigators aim to evaluate the effect of gastrectomy on pharmacokinetic profile of first-line anti-TB drugs in patients with pulmonary TB through this study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01364324
Study type	Observational
Source	National Cancer Center, Korea
Contact
Status	Completed
Phase
Start date	September 2010
Completion date	June 2020

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