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Trinucleotide Repeat Expansion clinical trials

View clinical trials related to Trinucleotide Repeat Expansion.

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NCT ID: NCT03862950 Recruiting - Clinical trials for Intellectual Disability

A Trial of Metformin in Individuals With Fragile X Syndrome (Met)

Start date: May 24, 2019
Phase: Phase 2
Study type: Interventional

This study is a controlled trial of metformin in individuals with fragile X syndrome between the ages of 6 and 35 years. Participants will be randomized in a double-blind design to either drug or placebo and will attend three visits to the study site in a 4-month period for a series of tests. The primary objectives are to assess safety, tolerability, and efficacy of metformin in the treatment of language deficits, behavior problems, and obesity/excessive appetite in individuals with fragile X syndrome.

NCT ID: NCT03479476 Completed - Clinical trials for Intellectual Disability

A Trial of Metformin in Individuals With Fragile X Syndrome

Met
Start date: April 30, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study is a controlled trial of metformin in individuals with fragile X syndrome between the ages of 6 and 25 years. Participants will be randomized in a double-blind design to either drug or placebo and will attend three visits to the study site in a 4-month period for a series of tests. The primary objectives are to assess safety, tolerability, and efficacy of metformin in the treatment of language deficits, behavior problems, and obesity/excessive appetite in individuals with fragile X syndrome.