Clinical Trials Logo
  1. Home
  2. Traumatic Injury
  3. NCT01485419

Characterization of the Early Sex Hormone Milieu Post Injury and Relationship With Resuscitation Requirements and Coagulopathy

Traumatic Injury Clinical Trial

Official title:
Characterization of the Early Sex Hormone Milieu Post Injury and Relationship With Resuscitation Requirements and Coagulopathy

Clinical Trial Summary

Traumatic injury is a major public health problem with an immense societal cost. Despite improvements in trauma management, patients continue to suffer significant morbidity and mortality. Evidence suggests that males and females tolerate severe injury differently with a greater protection afforded to females. Determining the mechanisms responsible for these sex-based outcome differences after injury, focusing specifically on the early sex-hormone environment post-injury, may allow those at highest risk for poor outcome to be predicted and promote interventions that can improve outcomes for all injured patients. The goal of this study is to determine if the early sex hormone environment soon after injury has effects on the intensity of the immune response, resuscitation and blood transfusion requirements, and important clinical outcomes including mortality, organ failure and infection, following significant injury.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01485419
Study type Observational
Source University of Pittsburgh
Contact
Status Completed
Phase N/A
Start date January 2011
Completion date December 2012
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04992130 - Sport Concussion Performance-Based Prevention Program N/A
Recruiting NCT05451394 - Prevention of Injury in Military Settings Through the Use of Body Awareness. N/A
Withdrawn NCT03928015 - Evaluation of Dronabinol For Acute Pain Following Traumatic Injury Phase 2
Recruiting NCT04588311 - ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients Phase 3
Recruiting NCT05437575 - Prehospital Analgesia INtervention Trial (PAIN) Phase 3
Recruiting NCT06034834 - Near-Infrared Imaging for Perfusion Assessment of Traumatic Soft Tissue and Skeletal Injuries N/A
Not yet recruiting NCT06366282 - Pediatric and Caregiver Traumatic Stress Intervention (PACTS) N/A
Recruiting NCT05568888 - Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study ) Phase 3
Completed NCT02412982 - Evaluation of Venous Thromboembolism Prevention in High-Risk Trauma Patients Phase 4
Withdrawn NCT01497678 - Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center N/A
Completed NCT05225441 - National Investigation in College and High School Among Adolescents on Health and Substances at the FSEF
Completed NCT03927729 - Use of Methoxyflurane (Penthrox) as an Antalgic in Hospital Trauma N/A
Not yet recruiting NCT06383650 - Use of 81 vs 325mg of ASA in Treatment of BCVI Early Phase 1
Completed NCT04778332 - Trottinettes Urgences 2019-2020
Recruiting NCT06404177 - Enantyum® IV Versus Piroxen® IM in Emergency Pain Management Phase 3
Recruiting NCT05086757 - Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors N/A
Completed NCT03628846 - Opioid Use After Traumatic Injury in Adolescents
Active, not recruiting NCT05320445 - A Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Trauma N/A
Completed NCT01771055 - Direct Peritoneal Resuscitation Effects in the Damage Control Patient N/A
Completed NCT04980937 - Peroneal Nerve Injury: a 20- Year Retrospective Case Series Study