Clinical Trials Logo

Clinical Trial Summary

For patients with breast cancer subject to a mastectomy, preserving the morphology of the breast with immediate reconstruction is a crucial aspect to preserve the quality of life. There are several types of breast reconstruction: prosthetic in one or two stages and autologous reconstruction. Adjuvant radiotherapy has shown an improvement of the overall survival and of the local control for patients with positive lymph nodes. Despite the undoubted cancer benefits, several studies have shown the negative impact of radiotherapy on breast reconstruction. However, there are few studies with a significant number that evaluate the effect of radiotherapy on the three types of reconstruction. In particular, given the extreme variability in clinical approaches, there is no certainty about the best reconstructive timing compared to radiotherapy, the iterations with dermic matrices as well as the usefulness of ancillary procedures such as autologous adipose grafting. The aim of this study is to compare retrospectively these three types of reconstruction techniques to evaluate the effect of radiotherapy on different reconstructive modes.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04783818
Study type Observational
Source Humanitas Clinical and Research Center
Contact
Status Completed
Phase
Start date June 6, 2020
Completion date January 25, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT05059379 - Medial vs. Entire Supraclavicular Lymph Node Radiation Therapy for Patients With Invasive Breast Cancer Phase 3
Recruiting NCT06197581 - Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer N/A
Recruiting NCT06042946 - Microsurgical Resection of Intramedullary Spinal Cord Metastases
Completed NCT04321187 - Influence of Prostate Cancer Radiation on Aging
Terminated NCT03553212 - Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy N/A
Completed NCT02979691 - Phase II/III Study Comparing Chemoradiotherapy With Radiotherapy in Elderly Patients With Esophageal or Esophagogastric Cancer - 3JECROG P-01 Phase 2/Phase 3
Terminated NCT03720158 - Enteral Omega 3 During Radiotherapy to Improve the Quality of Life and Functionality of Head and Neck Cancer Patients N/A
Not yet recruiting NCT05339581 - IMRT Plus PD-1 Blockade and Lenvatinib for HCC With PVTT (Vp3) Before Liver Transplantation N/A
Recruiting NCT05308732 - Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy Phase 1
Recruiting NCT06313450 - De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal Carcinoma N/A
Active, not recruiting NCT03893461 - Coagulation System In STereotactic Radiotherapy Of NSCLC
Active, not recruiting NCT03475186 - Testing Ramipril to Prevent Memory Loss in People With Glioblastoma Phase 2
Recruiting NCT06418113 - Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma Phase 1
Recruiting NCT04819685 - Application of KANG FU PEN in Radical Concurrent Radiotherapy and Chemotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Rectal Injury Phase 4
Completed NCT04854525 - Breast Reconstruction in Previously Irradiated Breast
Completed NCT03226925 - Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies N/A
Recruiting NCT04901234 - Adaptive RadioTherapy for OroPharynx Cancer Phase 2
Recruiting NCT06272617 - Acupuncture for Prevention and Treatment of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer N/A
Not yet recruiting NCT05561634 - Radiotherapy by Sonic Hedgehog Pathway Inhibitors in Basal Cell Carcinoma Phase 2
Not yet recruiting NCT03168048 - Oncologic Therapy Support Via Means of a Dedicated Mobile App N/A