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Clinical Trial Summary

This study is designed to evaluate the efficacy and safety of gemlapodect (NOE-105) on reducing tics associated with Tourette Syndrome (TS) in adults with TS. Adolescents will be enrolled after a sentinel cohort of adults is complete.


Clinical Trial Description

Gemlapodect is an investigational selective PDE10A inhibitor with a potential therapeutic effect for the treatment of tics associated with Tourette Syndrome (TS). This is a multi-center, double-blind, parallel-arm, placebo-controlled study in patients with TS. Following screening to confirm eligibility and to wash-out previous TS medication during a 14-day placebo run-in, patients will be randomized 1:1 on Day 1 to receive gemlapodect or placebo once daily for 12 weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06315751
Study type Interventional
Source Noema Pharma AG
Contact Noema Pharma
Phone please contact via email
Email clinicaltrials@noemapharma.com
Status Not yet recruiting
Phase Phase 2
Start date May 31, 2024
Completion date December 31, 2026

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