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NCT ID: NCT06450938 Not yet recruiting - Clinical trials for Apical Periodontitis

No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment

Start date: May 30, 2024
Phase: N/A
Study type: Interventional

Developing neural network-based models for image analysis can be time-consuming, requiring dataset design and model training. No-code AI platforms allow users to annotate object features without coding. Corrective annotation, a "human-in-the-loop" approach, refines AI segmentations iteratively. Dentistry has seen success with no-code AI for segmenting dental restorations. This study aims to assess radiographic features related to root canal treatment quality using a "human-in-the-loop" approach.

NCT ID: NCT06447519 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?

RCTCa(OH)2
Start date: September 2024
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effectiveness of calcium hydroxide as an intracanal medicament in the clinical and radiographic healing of periapical tissues in teeth diagnosed with symptomatic apical periodontitis. This evaluation will be conducted after multiple visit endodontic treatment. The follow-up sessions will be programmed from 6 to 24 months postoperatively. Postoperative pain will also be considered as a secondary outcome. Participants will be asked to rate their pain level on a numerical scale from 0 to10 before and after each session of endodontic treatment. Additionally, the use of analgesics after the procedure will be measured and the incidence of flare-ups will be evaluated. Two study groups will be formed to undergo multiple-visit endodontic treatment. The intervention group will receive intracanal medication of calcium hydroxide, while the control group will have the root canal left empty between appointments.

NCT ID: NCT06304259 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis

Start date: April 2024
Phase: N/A
Study type: Interventional

Problem statement: The post-operative pain after endodontic treatment. aim of study: The study is aiming to compare postoperative pain after submucosal cold saline injection (submucosal cryotherapy) (SMC) versus intra-canal cryotherapy (ICC) in mandibular single rooted premolars with symptomatic irreversible pulpitis with symptomatic apical periodontitis (SAP). The material and methods: Subjects and methods: sixty patients will be randomly divided into three groups: the SMC group, the ICC group, and the control group. The patients' postoperative pain will be recorded at 12, 24, and 48 hours postoperatively by questioning them. Quantification of substance P will be done using an ELISA test from peri-radicular fluid swab.

NCT ID: NCT06253767 Not yet recruiting - Pain, Postoperative Clinical Trials

Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation

Start date: February 20, 2024
Phase: N/A
Study type: Interventional

The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars. The sample will consist of 58 participants treated endodontically in a single session and randomly allocated to the PBM Group with conventional treatment with photobiomodulation and the Control Group with conventional treatment with simulation of PBM. The primary variable of the study will be the evaluation of spontaneous pain immediately before treatment, and the participant will be reassessed for postoperative pain 24 hours after instrumentation using the visual analog scale (VAS). As secondary variables, pain prevalence, pain at 4h, 8h, and 12h after the procedure, palpation pain (vestibular and lingual), and percussion pain (vertical and horizontal) will be assessed 24 hours after the procedure, as well as the number of necessary analgesics (paracetamol) and the impact of oral health on quality of life evaluated by the OHIP 14 instrument.

NCT ID: NCT06226870 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of NSRCT Versus VPT in Management of Teeth With Symptomatic Irreversible Pulpitis Associated With Apical Periodontitis

Start date: May 2024
Phase: N/A
Study type: Interventional

Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin. Clinically, pulpitis is termed as reversible or irreversible, whereas histologically, it is described as acute, chronic or hyperplastic . Pulpitis is considered reversible when the pulp can heal following conservative management . For such cases, a coronal pulpotomy is considered as a definitive treatment option having 78% to 90% of success rate . In irreversible pulpitis (IP), the pulp is not capable of healing, thus it is treated traditionally complete pulpectomy.

NCT ID: NCT06151665 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Single Rotary File System Versus Conventional Manual K-file in Pulpectomy of Primary Molars.

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The sample size will be divided between two groups, Group A pulpectomy will be done using single rotary file in primary molars and group B pulpectomy will be done using manual K file system. follow up of the patients and clinical and radiographical success rates of cases will be seen.

NCT ID: NCT05476419 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Apical Gap Length and Adaptation of Zirconia Post Using Intraoral and Extraoral Scan of Silicon Impression Technique

Start date: September 2023
Phase: N/A
Study type: Interventional

First, participants will undergo clinical and radiographic examination for taking all the needed preoperative records, then endodontically treated teeth preparation starting with removal of any carious or undermined tooth structure then ferrule preparation then followed by intra-radicular preparation and then placement of the provisional restoration. In the third visit we will take the final impression of the post space for each patient by using the intraoral scan and extraoral scan o f the conventional impression. Then assessment of the apical gap length by using digital periapical radiograph using the paralleling technique and assessment of post adaptation using replica technique followed by placement and permanent cementation of the zirconia custom made post and core restoration that showed less apical gap length and better adaptation then taking the final impression for the extracoronal restoration and finally permanent cementation of the extra coronal fixed restoration.

NCT ID: NCT05289973 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Effect of TruNatomy and HyFlex EDM Instrumentation on Postoperative Pain

TRN
Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The aim of the present study is to clinically compare the incidence of postoperative pain after root canal preparation using TruNatomy system and HyFlex Electrical Discharge Machined (EDM) rotary system in asymptomatic necrotic mandibular molars.

NCT ID: NCT04892355 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Postoperative Pain After İntracanal Procedures

Start date: August 6, 2022
Phase: N/A
Study type: Interventional

Aim: The aim of this study is to investigate the effects of different irrigation activation systems on pain after endodontic treatment in molar teeth with irreversible pulpitis.Post-operative pain values of the participants will be recorded and evaluated with the VAS scale. Postoperative pain values of the techniques will be compared with statistical evaluation.

NCT ID: NCT04738526 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

One Year Clinical Evaluation of Shade Matching and Patient Satisfaction of New Gradient Technology Monolithic Zirconia (5Y-TZP\3Y-TZP) Compared to Lithium Disilicate Crowns in Dental Esthetic Zone

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

Although zirconia is widely used for fabrication of restorations, the 3Y-TZP zirconia where limited for posterior region for its high strength and bad esthetic. While the 5Y-TZP zirconia is limited for the anterior region due to its good esthetic and low strength. For that reason, the introduction of the new gradient technology zirconia (5Y-TZP\3Y-TZP) (IPS e.max Zircad Prime) has offered a solution to solve this problem be combining the esthetic of 5Y-TZP and the high strength of 3Y-TZP. The aim of the present study is to evaluate shade matching to natural tooth and patient satisfaction of the new gradient technology zirconia (5Y-TZP\3Y-TZP) and lithium disilicate ceramic crowns.