Clinical Trials Logo

Clinical Trial Summary

Wisdom tooth extraction is the most common surgical procedure being carried out in oral surgical departments. The complications carried by post operative period include pain and trismus and may affect patient's quality of life.

PRP is an autologous concentrate of platelet in plasma and accelerate healing by production of growth factors. PRP is prepared from patient's own blood and later packed with gel sponge (Spongistone) in the experimental group immediately after surgical extraction of mandibular third molar teeth, followed by suture placement to close the surgical site.


Clinical Trial Description

Wisdom tooth extraction is the most common surgical procedure being carried out in oral surgical departments. The complications carried by post operative period includes pain, swelling, trismus , along with disturbance in post extraction wound healing which may significantly affect patient's quality of life.

PRP is an autologous concentrate of platelet suspended in plasma and accelerate healing by production of various growth factors. PRP is prepared from patient's own blood and later packed with gel sponge (Spongistone) in the experimental group immediately after surgical extraction of mandibular third molar teeth, followed by suture placement to close the surgical site. PRP speeds up healing by concentration of growth factors which can lessen the inflammation and decreases trismus and pain. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04452734
Study type Interventional
Source Foundation University Islamabad
Contact
Status Completed
Phase N/A
Start date July 21, 2015
Completion date May 14, 2016

See also
  Status Clinical Trial Phase
Completed NCT04166890 - Comparison of the Efficacy and Safety of Two Homologous Active Principles for Local Dental Anesthesia Phase 4
Active, not recruiting NCT02952209 - The Effect of Alveolar Ridge Preservation After Tooth Extraction in the Posterior Maxilla N/A
Completed NCT02155764 - Ridge Preservation With New Class of Osteoplastic Materials Phase 2
Completed NCT01588444 - Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft N/A
Completed NCT00387140 - A Study to Evaluate the Safety and Efficacy of an Investigational Drug in the Treatment of Postoperative Dental Pain (MK-2295-005) Phase 2
Recruiting NCT06245161 - Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients N/A
Recruiting NCT05615272 - Treatment of Alveolar Osteitis: Traditional or Regenerative? N/A
Completed NCT05101954 - Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants N/A
Completed NCT03985033 - The Clinical and Biological Effects of Leucocyte and Platelet-rich Fibrin (L-PRF) on Post-extraction Sockets Healing N/A
Completed NCT04082598 - Antibiotic Therapy in Erupted Tooth Extractions Phase 4
Completed NCT01924390 - Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft N/A
Completed NCT04930497 - Vestibular Socket Therapy With and Without Bone Grafting N/A
Completed NCT03191448 - Ridge Preservation Using FDBA and a Collagen Wound Dressing in Molar Sites N/A
Completed NCT03211312 - Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases
Not yet recruiting NCT06038695 - Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB N/A
Completed NCT05845437 - On Adequacy of Referrals to Oral and Maxillofacial Surgery
Recruiting NCT05220462 - Remimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extractions. Phase 3
Active, not recruiting NCT03943680 - Plasma Rich in Growth Factors in Post-extraction Sockets N/A
Recruiting NCT05106855 - Comparative Study of Immediate Single Unit Implants in Early Loading Protocols, With or Without Photobiomodulation. N/A
Completed NCT03487718 - A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study. N/A