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Tooth Diseases clinical trials

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NCT ID: NCT06280014 Completed - Tooth Diseases Clinical Trials

Evaluation of the Effects of Mefenamic Acid and Dexketoprofen on Postoperative Wisdom Dental Surgery

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

This study was administered to 22 female and 8 male patients. Patients with impacted wisdom teeth on both sides of the mandible were selected. After impacted tooth extraction, the patient used mefenamic acid on one side and dexketoprofen on the other side for postoperative pain relief. The effects of these two materials on patient comfort were investigated.

NCT ID: NCT06112366 Completed - Tooth Diseases Clinical Trials

Comparison of Silk Suture and Tissue Adhesive for Wound Closure After Impacted Tooth

Start date: May 20, 2022
Phase: N/A
Study type: Interventional

This study was administered to 21 female and 9 male patients. Patients with impacted wisdom teeth on both sides of the mandible were selected. After extraction of the impacted teeth, silk sutures were used on one side and cyanoacrylate tissue adhesive on the other side for wound closure. The effects of these two materials on patient comfort were investigated.

NCT ID: NCT06067542 Completed - Tooth Diseases Clinical Trials

Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction

Start date: March 4, 2020
Phase: N/A
Study type: Interventional

In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery. Similarly positioned fully impacted impacted lower third molars were extracted. Bilateral impacted wisdom teeth of the patients were randomly selected. After the operation, the experimental group received Dentasave 0.2% chlorhexidine toothpaste containing chlorhexidine and the control group received toothpaste with the same content but without chlorhexidine. Teeth were extracted by the same dentist at 14-day intervals. For microbiological analysis, saliva samples were taken before the first tooth extraction, before the second tooth extraction 14 days later and on the 28th day and sent to the microbiology laboratory. Wound healing, edema and trismus in both extractions were evaluated 1 week after tooth extraction. Wound healing was evaluated as good, acceptable and poor. VAS (Visual Analog Scale) was used for pain assessment and recorded 14 days after tooth extraction.

NCT ID: NCT05519462 Completed - Tooth Diseases Clinical Trials

Low-Dose CBCT Protocol for Pre-Surgical Evaluation of the Mandibular Third Molar, a Feasible Choice?

Start date: August 1, 2020
Phase:
Study type: Observational

Low-Dose CBCT Protocol for Pre-Surgical Evaluation of the Mandibular Third Molar. CBCT investigations with standard and low dose protocol for evalutation of the mandibular third molar.

NCT ID: NCT05484401 Completed - Tooth Diseases Clinical Trials

Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars

Start date: August 9, 2022
Phase: Phase 3
Study type: Interventional

This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2 x 200 mg Ibuprofen Liquid Capsules in subjects with post-operative dental pain.

NCT ID: NCT05361031 Completed - CMT Clinical Trials

The Safety and Tolerability of Engensis (VM202) in Patients With Charcot-Marie-Tooth Disease Subtype 1A (CMT1A)

Start date: September 21, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

To assess the safety and tolerability of the investigational product (VM202) injected in the weakened lower limb muscles of CMT1A patients

NCT ID: NCT05333406 Completed - Clinical trials for Charcot-Marie-Tooth Disease, Type IA

Determine the Safety and Dose of EN001 in Patients With Charcot-Marie-Tooth Disease (CMT) Type 1A

Start date: February 22, 2022
Phase: Phase 1
Study type: Interventional

Open-label, Dose-escalation, Phase 1 Clinical Trial to Determine the Safety and Dose of EN001 in Patients with Charcot-Marie-Tooth disease (CMT) type 1A

NCT ID: NCT04980807 Completed - Clinical trials for Charcot-Marie-Tooth Disease

Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy Controls

ESTABLISH
Start date: April 7, 2021
Phase:
Study type: Observational

The primary aim of this study is to discover whether patients with CMT type 1 and 2 have neuromuscular junction transmission deficits. The secondary aim is to collect information of different clinical and electrophysiological test procedures to perform possible future clinical trials in CMT patients.

NCT ID: NCT04853121 Completed - Tooth Diseases Clinical Trials

Accuracy and Primary Stability of Straight and Tapered Implants in Immediate Implant Placement Using Dynamic Navigation

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Prosthetic-driven immediate implant placement for optimal aesthetic restoration has been increasing in demand during the last decades but requires higher accuracy. Dynamic navigation has been a reported better implant positioning. There are two main choices of implant macrogeometry: straight and tapered implants. One feature of implant design that may influence implants' accuracy is the taper of the implant body. However, their exact role is still needed to be investigated further. Besides, implant macrogeometry may influence primary stability, which is a prerequisite in achieving osseointegration. Therefore, we designed a randomized controlled clinical trial study to verify the clinical efficacy of the implant macrogeometry by comparing straight implants with tapered implants in immediate implant placement using dynamic navigation.

NCT ID: NCT04827693 Completed - Periodontitis Clinical Trials

The Cortical Shield for Facial Bone Reconstruction

Start date: January 3, 2019
Phase:
Study type: Observational

To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.