Tobacco Use Clinical Trial
Official title:
Early Tobacco Abstinence in High Risk Smokers
This proposal will conduct a prospective examination of the clinical course (intensity, content and duration) of tobacco (nicotine) abstinence effects in male and female smokers who are either heavy/light alcohol drinkers with/without depressive symptoms.
1. To compare male and female smokers, with and without current depressive symptoms, in a
prospective study of the intensity, content & duration of nicotine abstinence effects
during an eight-day abstinence period, and responses to cue exposure (invivo cigarette
cues, alcohol and negative affect-inducing imagery cues) during acute vs. prolonged
abstinence and,
2. To compare male and female smokers, who are either heavy alcohol drinkers or light
alcohol drinkers, in a prospective study of the intensity, content & duration of
nicotine abstinence effects during an eight-day abstinence period, and responses to cue
exposure (invivo cigarette cues, alcohol and negative affect-inducing imagery cues)
during acute vs. prolonged abstinence.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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