Tinnitus Clinical Trial
Official title:
Transcranial Direct Current Stimulation (tDCS) for the Treatment of Chronic Subjective Tinnitus
The purpose of this study is to determine if repeated sessions of transcranial direct current stimulation (tDCS) are effective for treating chronic subjective tinnitus. Previous studies have reported brief improvements in tinnitus after safe and noninvasive stimulation of the auditory cortex or limbic system. The investigators hypothesize that a greater improvement in tinnitus will be achieved following repeated sessions of tDCS that target both auditory and limbic systems.
Subjective tinnitus is a distressing condition characterized by the sensation of sound or
noise in the absence of internal or external stimuli. Research indicates that tinnitus may
develop due to maladaptive plastic changes in the auditory cortex and limbic system. These
changes can be targeted using safe and noninvasive brain stimulation techniques like
transcranial direct current stimulation (tDCS). TDCS alters the excitability of the cortex
using a weak direct current and may lead to long-term plastic changes, making it a potential
therapeutic tool for the treatment of tinnitus.
Transient improvements in tinnitus have been reported after inhibitory stimulation of the
auditory cortex and after excitatory stimulation of the prefrontal cortex, however the
effects of a combined stimulation paradigm remain unknown. The investigators hypothesize
that a cumulative effect will be observed following repeated sessions of tDCS by modulating
both the excitability of the auditory cortex and prefrontal cortex.
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Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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