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Tinnitus clinical trials

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NCT ID: NCT05467059 Completed - Tinnitus Clinical Trials

Evaluation of Potential Causes of Nap Modulated Tinnitus

TinniNap
Start date: June 9, 2022
Phase:
Study type: Observational [Patient Registry]

The proposed research is a non-interventional study made to evaluate different measurements on 1 group of participants, before and after taking a nap, aiming to potentially guide future investigations on nap-modulated tinnitus to better understand this phenomenon. The main hypothesis is that sleep apneas could be correlated with an increase of tinnitus intensity.

NCT ID: NCT05453019 Recruiting - Tinnitus Clinical Trials

Effects of CI on Tinnitus and Its Symptoms

Start date: July 4, 2022
Phase: N/A
Study type: Interventional

Abnormal activity in the central auditory system is the cause of subjective experience of tinnitus. Electrical stimulation can inhibit the abnormal activity of auditory related neurons in patients with tinnitus. In recent years, the application of electrical stimulation in the treatment of tinnitus is a hot research topic, and has made some progress. However, its treatment is still in the discussion stage, and there is no best scheme suitable for clinical practice. At present, scholars have found that cochlear electrode stimulation can inhibit tinnitus, but its mechanism is not clear. It is difficult to locate the origin of tinnitus, and the location of electrode stimulation and stimulation parameters still need to be further optimized. Because the implanted part of the cochlear implant contains magnets, the patients cannot perform functional MRI. However, the prevalence of tinnitus in this group is very high (67.0~100.0%, with an average of 80.0%), so it is of great value and significance to study the effect of tinnitus treatment in such patients. In this study, a new clinical electroencephalogram (EEG) technique was used to make up for the lack of MRI imaging in patients with electrode implantation. EEG analyzes the functional connection of different brain regions through EEG test electrodes, uses the traceability function of EEG software to locate the location of tinnitus, analyzes the process of tinnitus inhibition by electrical stimulation, and explains the mechanism of tinnitus inhibition by electrical stimulation from a new perspective.

NCT ID: NCT05441540 Completed - Pulsatile Tinnitus Clinical Trials

Internal Jugular Vein Compression Collar for Novel Symptomatic Treatment of Venous Pulsatile Tinnitus

Start date: October 27, 2022
Phase: N/A
Study type: Interventional

This study seeks to pilot an evaluation of whether an external jugular vein compression collar approved by the US Food and Drug Administration (FDA) for contact sports can provide symptomatic relief of venous pulsatile tinnitus. Furthermore, the study will evaluate quality of life impacts of the device and adherence by users.

NCT ID: NCT05437185 Completed - Tinnitus Clinical Trials

Long-term tDCS Tinnitus Treatment

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The study was designed to evaluate a therapeutic effect of tDCS in the treatment of tinnitus and its comorbidities (anxiety, depresion) and to evaluate the associated quality of life. In the randomized, double-blinded, sham-controlled trial, 39 participants (active n=19, sham n=20) underwent bilateral dorsolateral prefrontal cortex (DLPFC) tDCS (anode over right DLPFC, cathode left DLPFC, current of 1.5 mA, 20 minutes, 6 sessions in 2 weeks). Tinnitus Functional Index (TFI), Iowa Tinnitus Handicap Questionnaire (ITHQ), Beck Anxiety Inventory (BAI), Zung Self-Rating Depression Scale (SDS), and WHO-Quality of Life-BREF were employed in 4 evaluation points, including the follow-ups of 6 weeks and six months.

NCT ID: NCT05434637 Recruiting - Tinnitus Clinical Trials

Somatosensory Tinnitus RCT

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to learn more about a type of tinnitus (ringing in the ears) known as "somatosensory tinnitus." This type of tinnitus is suspected when the tinnitus perception changes following head and/or neck movements. This study is also exploring a possible way to treat somatosensory tinnitus.

NCT ID: NCT05417711 Not yet recruiting - Clinical trials for Tinnitus, Subjective

Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

This clinical study is a prospective, multicenter, randomized, controlled, double-blind clinical study. Sun Yat Sen Memorial Hospital of Sun Yat sen University was the central unit, and Nanjing First Hospital, Sun Yat Sen people's Hospital, Guanfzhou Panyu central Hospital and Zhuhai integrated traditional Chinese and Western medicine hospital were the cooperative units. In this study, 388 patients with chronic subjective tinnitus were recruited. In view of chronic subjective tinnitus, a common ear disease, the study gave the patients three months of treatment with transcutaneous vagus nerve stimulation paired with tailor-made notched music therapy or tailor-made notched music training alone. By comparing the changes of subjective scale scores related to tinnitus before and after treatment in patients receiving two different therapies, such as THI, VAS, BAI, BDI, PSQI, to evaluate the efficacy of the two therapies, so as to judge whether transcutaneous vagus nerve stimulation paired with tailor-made notched music therapy is better than tailor-made notched music training alone. In addition, the study will continue to follow up the patients after the treatment for one year to observe the difference in the long-term sustained efficacy of the two therapies. This clinical study will also evaluate the two therapies from the perspective of compliance and safety, and explore the factors that affect the efficacy of the two therapies.

NCT ID: NCT05402228 Completed - Tinnitus Clinical Trials

Investigation of the Aural Symptoms and Dizziness in Patients With Temporomandibular Joint Disorders

Start date: March 27, 2022
Phase:
Study type: Observational [Patient Registry]

120 male and female patients aged between 18-65 years who apply to the outpatient clinic and diagnosed with TMD will be included in the study. Patients will be divided into 3 groups as Muscle Disorders (Group 1), Temporomandibular Joint Disorders (Group 2) and degenerative joint diseas (osteoarthrosis) (Group 3) according to DC/TMD axis I diagnostic criteria. maximum mouth opening, TMJ sound, pain levels, tinnitus, and dizziness are evaluated.

NCT ID: NCT05374421 Terminated - Tinnitus Clinical Trials

Efficacy of the Erchonia Corporation THLâ„¢ for Providing Relief of Tinnitus Symptoms

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to determine the effectiveness of the Erchonia® THLâ„¢, manufactured by Erchonia Corporation (the Company), for prescription home use in providing relief of tinnitus symptoms when used by individuals in their own homes.

NCT ID: NCT05343026 Not yet recruiting - Clinical trials for Tinnitus, Subjective

Efficacy of Hearing-aid Treatment for Patients With Tinnitus and Co-existing Hearing Loss

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Considering the extent to which HAs play a role in sound perception and residual hearing preservation among patients with tinnitus and co-existing HL remains a lack of compelling extensive evidence, investigators designed this single-blind, 6-months randomized, controlled trial with two parallel groups. One is the HA treatment group, and the other is the waiting list control (WLC) group which receives no interventions during this period.

NCT ID: NCT05338684 Not yet recruiting - Clinical trials for Pulsatile Tinnitus (Diagnosis)

Role of the Radiologist in Management of Pulsatile Tinnitus

Start date: April 17, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.