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Tinnitus clinical trials

View clinical trials related to Tinnitus.

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NCT ID: NCT04335812 Completed - Tinnitus Clinical Trials

Internet-based Cognitive Behavioral Therapy for Tinnitus Sufferers

ICBT
Start date: May 4, 2020
Phase: N/A
Study type: Interventional

Nearly 50 million people in the U.S. experience tinnitus, of which about 20 million people have burdensome chronic tinnitus. Tinnitus can be very debilitating as many aspects of daily life can be affected, such as sleep, mood, and concentration. Currently, there is no cure for tinnitus. Pharmacological or sound-therapy based interventions are sometimes provided but may be of limited value to certain individuals. Research suggests that Cognitive Behavior Therapy (CBT) based approaches have the most evidence of effectiveness in the management of tinnitus. However, CBT is rarely offered to tinnitus sufferers in the U.S. (less than 1%), partly because of lack of trained professionals who can deliver CBT. To improve access to CBT for tinnitus, an online CBT program has been developed. The purpose of this study is to evaluate if the full CBT administered via the Internet results in better outcomes when compared to relaxation only CBT administered via the Internet for adults with tinnitus in the United States.

NCT ID: NCT04310605 Completed - Clinical trials for Tinnitus, Subjective

Effectiveness of Specialised Cognitive Behavioural Therapy (CBT) for Tinnitus.

Start date: January 1, 2014
Phase:
Study type: Observational

This is an observational study of specialised CBT for tinnitus for adults delivered in routine care.

NCT ID: NCT04296097 Recruiting - Clinical trials for Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus

Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)

TINNOP3-DBS
Start date: April 23, 2021
Phase: N/A
Study type: Interventional

This pilot study aims at evaluating the effectiveness of the treatment of unilateral or bilateral, non-pulsatile, disabling, tinnitus, without vestibular dysfunction, using Deep Brain Stimulation (DBS) of the parieto-insular right operculum 3 (OP3) in a cross-over, double study design.

NCT ID: NCT04281953 Completed - Cancer Clinical Trials

Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors

Start date: September 5, 2019
Phase:
Study type: Observational

This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on quality of life will be investigated. From this, we can identify the specific needs of patients experiencing hearing loss and tinnitus following chemotherapy and develop a tailored and personalised support system.

NCT ID: NCT04270916 Suspended - Cancer Clinical Trials

Prevalence and Impact on QoL From Ototoxicity in Cancer Survivors

Start date: February 3, 2020
Phase:
Study type: Observational

This study will involve collaborating with oncologists in the post-chemotherapy follow-up appointments. The participants who wish to consent to this study will then answer 3 short questionnaires (THI, HHIA and SF-36) about hearing loss, tinnitus and quality of life. The audiologist or the researcher, under the supervision of an audiologist, will then perform a simple, non-invasive hearing test on the participant. Should the participant have a hearing loss, they will be advise to seek help from their General Practitioner.

NCT ID: NCT04262050 Completed - Depression Clinical Trials

Combined tDCS and TMS on Subjective Tinnitus and Combined Depression

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

The investigators combined transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) to increase the effective response of a single session of neuromodulation in subjective tinnitus.

NCT ID: NCT04226456 Terminated - Tinnitus Clinical Trials

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

Start date: July 10, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacity of N-acetylcystein against Cisplatin-induced ototoxicity.

NCT ID: NCT04210310 Terminated - Tinnitus Clinical Trials

High Dose Oxytocin Nasal Spray for Treatment of Tinnitus

Start date: January 15, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effects of high-dose intranasal oxytocin for treating tinnitus. The hypothesis is that high dose intranasal oxytocin can significantly reduce tinnitus severity and disability.

NCT ID: NCT04192773 Recruiting - Tinnitus Clinical Trials

An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus

Start date: April 28, 2021
Phase: Early Phase 1
Study type: Interventional

This is an exploratory pilot open-label study to identify the signal changes on fMRI of patients with tinnitus and with temporary suppression of the tinnitus with IV lidocaine. Patients will include those with hearing loss (both unilateral and bilateral) and tinnitus, subjects with normal hearing and tinnitus, and control subjects with normal hearing and no tinnitus. Eligible subjects will have functional and subjective data collected at baseline, receive an IV lidocaine infusion, and have functional and subjective data collected post-infusion for comparison and identification of involved neural networks.

NCT ID: NCT04162405 Recruiting - Hearing Loss Clinical Trials

Tinnitus in Patients With and Without Sensorineural Hearing Loss

Start date: November 1, 2019
Phase:
Study type: Observational

The aim of this study is to evaluate hearing characteristics in patients with and without tinnitus using DPOAE and specific tinnitus severity index (TSI) and tinnitus handicap inventory (THI) questionnaires in both groups. Purpose of the research: Demonstrate that the characteristics of tinnitus depend on the presence and magnitude of hearing loss. Research participants: 150 patients coming for further audiological treatment due to tinnitus. Data will be collected from an electronic database that is filled in during diagnostic processing. During the diagnostic processing, TSI and THI questionnaires will be filled in, a tone audiogram (TA) and DPOAE will be performed.